ID F1ND44_CHICK Unreviewed; 552 AA.
AC F1ND44;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Polypyrimidine tract binding protein 3 {ECO:0000313|Ensembl:ENSGALP00010007777.1};
GN Name=PTBP3 {ECO:0000313|Ensembl:ENSGALP00010007777.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010007777.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010007777.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010007777.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_004949572.1; XM_004949515.2.
DR RefSeq; XP_015136187.1; XM_015280701.1.
DR RefSeq; XP_015136188.1; XM_015280702.1.
DR RefSeq; XP_015136189.1; XM_015280703.1.
DR RefSeq; XP_015136190.1; XM_015280704.1.
DR RefSeq; XP_424912.3; XM_424912.5.
DR AlphaFoldDB; F1ND44; -.
DR SMR; F1ND44; -.
DR STRING; 9031.ENSGALP00000072287; -.
DR PaxDb; 9031-ENSGALP00000025221; -.
DR Ensembl; ENSGALT00010013215.1; ENSGALP00010007777.1; ENSGALG00010005519.1.
DR GeneID; 427333; -.
DR KEGG; gga:427333; -.
DR CTD; 9991; -.
DR VEuPathDB; HostDB:geneid_427333; -.
DR GeneTree; ENSGT01050000244924; -.
DR InParanoid; F1ND44; -.
DR OMA; LQYADAM; -.
DR OrthoDB; 4825346at2759; -.
DR Proteomes; UP000000539; Chromosome Z.
DR Bgee; ENSGALG00000015669; Expressed in spermatocyte and 13 other cell types or tissues.
DR ExpressionAtlas; F1ND44; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0043484; P:regulation of RNA splicing; IBA:GO_Central.
DR CDD; cd12693; RRM2_PTBP1_like; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR006536; HnRNP-L/PTB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR021790; PTBP1-like_RRM2.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01649; hnRNP-L_PTB; 1.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR PANTHER; PTHR15592:SF17; POLYPYRIMIDINE TRACT-BINDING PROTEIN 3; 1.
DR Pfam; PF13893; RRM_5; 1.
DR Pfam; PF11835; RRM_8; 1.
DR SMART; SM00360; RRM; 4.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 4.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:F1ND44};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 77..151
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 200..286
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 358..432
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 475..550
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 552 AA; 60359 MW; 9CE473439D1AD373 CRC64;
MQEEMTSEDE TKQTTEEGEE DLVTDVSDDG FKHGPDNLLS SSVSGKPLTV SNSTPAKGGG
NDNKKLKGGR LPCLPSRVLH LRQIPDNATE ADVISLGLPF GKVTNVLILR GKSQAFLEMA
SEENAVSMVN YCSTAIPHIH NQPVYVQYSN HRELKTDSLP SQASAQAALQ VVNTVQCGNV
GVTSTFAAES GLPPGHSSVL RIIIENLFYP VSLEVLYQIF SKFGFVLKIV TFTRNNQFQA
LIQYAEPVNA YYAKMALNGR NIYNACCTLH IDFSKLTSLK VKYNNEKSRD FTRFDLPAAD
GQLPLDPAII AAFGSQGIIF QPYVGTGGIG PVTYFPQGAV TTSVASVRMS NPGVPGNSVL
LVSNLNPEAI TPHGLFILFG AYGDVLRVKI MFKNKENALV QMADATQAQI AISNLNGQKL
YGKFIRATLS KHQNIQLPRE GEEDNGLTKD YSNSPLHRFK NPGSKNFQNI FPPSATLHLS
NIPPSVSFDD LKSLFARTGS TVKAFRFFQR DCKMALIQLG SVEEAVHALI ELHNYDLGEN
HHLRVSFSKS TI
//
