ID F1NLB5_CHICK Unreviewed; 296 AA.
AC F1NLB5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Kazal type serine peptidase inhibitor domain 1 {ECO:0000313|Ensembl:ENSGALP00010025470.1};
GN Name=KAZALD1 {ECO:0000313|Ensembl:ENSGALP00010025470.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010025470.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010025470.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010025470.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_421724.1; XM_421724.5.
DR AlphaFoldDB; F1NLB5; -.
DR PaxDb; 9031-ENSGALP00000012705; -.
DR Ensembl; ENSGALT00010042980.1; ENSGALP00010025470.1; ENSGALG00010017786.1.
DR GeneID; 423856; -.
DR CTD; 81621; -.
DR VEuPathDB; HostDB:geneid_423856; -.
DR GeneTree; ENSGT00530000063555; -.
DR InParanoid; F1NLB5; -.
DR OMA; TWNITGQ; -.
DR OrthoDB; 3019991at2759; -.
DR Proteomes; UP000000539; Chromosome 6.
DR Bgee; ENSGALG00000007837; Expressed in spleen and 6 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0005614; C:interstitial matrix; IBA:GO_Central.
DR GO; GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR GO; GO:0009966; P:regulation of signal transduction; IBA:GO_Central.
DR CDD; cd00104; KAZAL_FS; 1.
DR Gene3D; 3.30.60.30; -; 1.
DR Gene3D; 4.10.40.20; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR000867; IGFBP-like.
DR InterPro; IPR011390; IGFBP_rP_mac25.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR PANTHER; PTHR14186; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR14186:SF21; KAZAL-TYPE SERINE PROTEASE INHIBITOR DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF00219; IGFBP; 1.
DR Pfam; PF07648; Kazal_2; 1.
DR PIRSF; PIRSF018239; IGFBP_rP_mac25; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00280; KAZAL; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51323; IGFBP_N_2; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
SQ SEQUENCE 296 AA; 32658 MW; 4789913ED3DC8040 CRC64;
MPVVLSSSCL LLYLLTLPWA CLQPGRAFPS SAEYLQRGWQ RLLEEGEGCA ECRPEECPVP
RGCLAGTVRD ACDCCWECAN LEGQICDLDN TNHFYGKCGE HLECQLEAGD LQRGEVPEPQ
CACISHQALC GSDGRTYPQI CRFLESARAH PDANLTVAHE GPCEAEPQIT SPPYDAWNVT
GQDVIFGCEV FAYPMASIEW RKDGTEMLLP GDDPHISVQF RGGPQKYEVT GWLQIQGVRV
TDEGTYRCFA RNRVGAVVAV ASLTVLTPDQ LNLTGLSLLE PRAVPEDYGD SEEEYY
//
