ID F1NML9_CHICK Unreviewed; 468 AA.
AC F1NML9;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 3.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=RAR related orphan receptor A {ECO:0000313|Ensembl:ENSGALP00010036927.1};
GN Name=RORA {ECO:0000313|Ensembl:ENSGALP00010036927.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00010036927.1, ECO:0000313|Proteomes:UP000000539};
RN [1] {ECO:0000313|Ensembl:ENSGALP00010036927.1}
RP IDENTIFICATION.
RC STRAIN=broiler {ECO:0000313|Ensembl:ENSGALP00010036927.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|RuleBase:RU004334}.
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DR RefSeq; XP_015134374.1; XM_015278888.1.
DR AlphaFoldDB; F1NML9; -.
DR PaxDb; 9031-ENSGALP00000005957; -.
DR Ensembl; ENSGALT00010060167.1; ENSGALP00010036927.1; ENSGALG00010024646.1.
DR VEuPathDB; HostDB:geneid_415377; -.
DR GeneTree; ENSGT00940000157387; -.
DR OrthoDB; 3475284at2759; -.
DR Proteomes; UP000000539; Chromosome 10.
DR Bgee; ENSGALG00000003759; Expressed in cerebellum and 12 other cell types or tissues.
DR ExpressionAtlas; F1NML9; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0004879; F:nuclear receptor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06968; NR_DBD_ROR; 1.
DR CDD; cd06939; NR_LBD_ROR_like; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR044101; NR_DBD_ROR.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR003079; ROR_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR45805; NUCLEAR HORMONE RECEPTOR HR3-RELATED; 1.
DR PANTHER; PTHR45805:SF3; NUCLEAR RECEPTOR ROR-ALPHA; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR01293; RORNUCRECPTR.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|RuleBase:RU004334};
KW Reference proteome {ECO:0000313|Proteomes:UP000000539};
KW Transcription {ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|RuleBase:RU004334}.
SQ SEQUENCE 468 AA; 53524 MW; DB39186714DF832E CRC64;
MMCFVLAAMK AQIEIIPCKI CGDKSSGIHY GVITCEGCKG FFRRSQQSNA TYSCPRQKNC
LIDRTSRNRC QHCRLQKCLA VGMSRDAVKF GRMSKKQRDS LYAEVQKHRM QQQQRDHQQQ
PGEAEPLTPT YNITTNGLTE LHDDLSNYID GHTPEGSKAD SAVSSFYLDI QPSPDQSGLD
INGIKPEPIC DYTPASGFFP YCSFTNGETS PTVSMAELEH LAQNISKSHM ETCQYLREEL
QQITWQTFLQ EEIENYQNKQ REVMWQLCAV KITEAIQYVV EFAKRIDGFM ELCQNDQIVL
LKAGSLEVVF IRMCRAFDSQ NNTVYFDGKY ASPEVFKSLG CEDFISFVFE FGKSLCSMHL
TEDEIALFSA FVLMSADRSW LQEKVKIEKL QQKIQLALQH VLQKNHREDG ILTKLICKVS
TLRALCGRHT EKLIAFKAIY PDIVRLHFPP LYKELFTSEF EPAMQIDG
//
