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Database: UniProt
Entry: F1QB08_DANRE
LinkDB: F1QB08_DANRE
Original site: F1QB08_DANRE 
ID   F1QB08_DANRE            Unreviewed;       514 AA.
AC   F1QB08; F1QUB3;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   20-JUN-2018, entry version 59.
DE   SubName: Full=BAI1-associated protein 2a {ECO:0000313|Ensembl:ENSDARP00000085613};
GN   Name=baiap2a {ECO:0000313|Ensembl:ENSDARP00000085613,
GN   ECO:0000313|ZFIN:ZDB-GENE-060421-2756};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000085613, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|Ensembl:ENSDARP00000085613}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000085613};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000085613, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000085613,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
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DR   EMBL; BX547935; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BX908776; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CT573495; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PRIDE; F1QB08; -.
DR   Ensembl; ENSDART00000091180; ENSDARP00000085613; ENSDARG00000062799.
DR   ZFIN; ZDB-GENE-060421-2756; baiap2a.
DR   eggNOG; ENOG410IKMM; Eukaryota.
DR   eggNOG; ENOG41110CD; LUCA.
DR   GeneTree; ENSGT00390000005995; -.
DR   InParanoid; F1QB08; -.
DR   OMA; EDYSPWA; -.
DR   TreeFam; TF325648; -.
DR   Reactome; R-DRE-2029482; Regulation of actin dynamics for phagocytic cup formation.
DR   Reactome; R-DRE-4420097; VEGFA-VEGFR2 Pathway.
DR   Reactome; R-DRE-5663213; RHO GTPases Activate WASPs and WAVEs.
DR   Proteomes; UP000000437; Chromosome 3.
DR   Bgee; ENSDARG00000062799; -.
DR   ExpressionAtlas; F1QB08; baseline and differential.
DR   GO; GO:0015629; C:actin cytoskeleton; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.
DR   GO; GO:0051764; P:actin crosslink formation; IBA:GO_Central.
DR   GO; GO:0051017; P:actin filament bundle assembly; IBA:GO_Central.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IBA:GO_Central.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IBA:GO_Central.
DR   CDD; cd11915; SH3_Irsp53; 1.
DR   Gene3D; 1.20.1270.60; -; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR013606; I-BAR_dom.
DR   InterPro; IPR030128; IRSp53.
DR   InterPro; IPR027681; IRSp53/IRTKS/Pinkbar.
DR   InterPro; IPR035594; Irsp53_SH3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR14206; PTHR14206; 1.
DR   PANTHER; PTHR14206:SF3; PTHR14206:SF3; 1.
DR   Pfam; PF08397; IMD; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF103657; SSF103657; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   PROSITE; PS51338; IMD; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW   SH3 domain {ECO:0000256|PROSITE-ProRule:PRU00192,
KW   ECO:0000256|SAAS:SAAS00989295}.
FT   DOMAIN        7    256       IMD. {ECO:0000259|PROSITE:PS51338}.
FT   DOMAIN      391    454       SH3. {ECO:0000259|PROSITE:PS50002}.
FT   COILED      133    153       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   514 AA;  57082 MW;  EDA126BFBD274098 CRC64;
     MVLSEDSTMS RTDEVHRISE NVYKNIMEQF NPCLRNFIAM GKNYEKALSS VTFAAKGYFD
     ALVRMGELAS ESQGSKDLGD VLFQMAEVHR QIQVQLEDML KCFHNELLSE LEKKVDLDAR
     YLTAALKKYQ IEHKSKGESL EKCQAELKKL RRKSQGSKNP SKYGEKELQY VEAISSKQSE
     LDTFIAEGYK TALSEERRRY CFLVDRQCAV AKNSSAYHGK GKDLLTQKIP VWQQACSDPN
     KLPDRAMMLT QQMTSGTSTL LSSPLHSSKG NLVISDPIPG AQPLPVPPEL AAFMGGGLGQ
     GRLMGPNGMS LVNGTTGVHG DDYWTDGVSQ GRPPSPQNPS QTQSQPQRQV SDVYSNTLPV
     RRPQPAKNKT TVGETRTLPR SSSMAAGLEK NGRSRVQAIF SHAAGDNSTL LSFTEGDIIT
     LLVPEARDGW HYGENEKNKM RGWFPFSYTR VLPDSDGEKL RVNLHHGKSS STGNLLERED
     MSLPMPDYGL TARLLAQSLT QSRQRPYSMA GFAQ
//
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