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Database: UniProt
Entry: F1QCP6_DANRE
LinkDB: F1QCP6_DANRE
Original site: F1QCP6_DANRE 
ID   F1QCP6_DANRE            Unreviewed;       262 AA.
AC   F1QCP6;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   16-OCT-2019, entry version 56.
DE   RecName: Full=Tafazzin family protein {ECO:0000256|RuleBase:RU365062};
GN   Name=taz {ECO:0000313|Ensembl:ENSDARP00000120241,
GN   ECO:0000313|ZFIN:ZDB-GENE-030131-684};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000120241, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|Ensembl:ENSDARP00000120241}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000120241};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000060717}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000060717};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000120241, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000120241,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
CC   -!- SIMILARITY: Belongs to the taffazin family.
CC       {ECO:0000256|RuleBase:RU365062}.
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DR   EMBL; CR354596; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 7955.ENSDARP00000120241; -.
DR   Ensembl; ENSDART00000060718; ENSDARP00000060717; ENSDARG00000041421.
DR   Ensembl; ENSDART00000140861; ENSDARP00000120241; ENSDARG00000041421.
DR   ZFIN; ZDB-GENE-030131-684; taz.
DR   eggNOG; KOG2847; Eukaryota.
DR   eggNOG; ENOG410XT5T; LUCA.
DR   GeneTree; ENSGT00390000018621; -.
DR   OMA; VYNKHII; -.
DR   TreeFam; TF313862; -.
DR   Reactome; R-DRE-1268020; Mitochondrial protein import.
DR   Reactome; R-DRE-1482798; Acyl chain remodeling of CL.
DR   Proteomes; UP000000437; Chromosome 23.
DR   Bgee; ENSDARG00000041421; Expressed in 34 organ(s), highest expression level in liver.
DR   ExpressionAtlas; F1QCP6; baseline and differential.
DR   GO; GO:0005739; C:mitochondrion; IEA:GOC.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
DR   GO; GO:0035965; P:cardiolipin acyl-chain remodeling; IBA:GO_Central.
DR   GO; GO:0007507; P:heart development; IMP:ZFIN.
DR   GO; GO:0001947; P:heart looping; IMP:ZFIN.
DR   GO; GO:0007007; P:inner mitochondrial membrane organization; IBA:GO_Central.
DR   GO; GO:0045823; P:positive regulation of heart contraction; IMP:ZFIN.
DR   InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR   InterPro; IPR000872; Tafazzin.
DR   PANTHER; PTHR12497; PTHR12497; 1.
DR   Pfam; PF01553; Acyltransferase; 1.
DR   PRINTS; PR00979; TAFAZZIN.
DR   SMART; SM00563; PlsC; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   DOMAIN       63    187       PlsC. {ECO:0000259|SMART:SM00563}.
SQ   SEQUENCE   262 AA;  30574 MW;  7CB510E5D3292C33 CRC64;
     MPLEVTWPFP QCPRLGWRIS SRVVMGMVGS YSYLWTKYFN SLMVHNQDVL LNLVDERPQD
     TPLITVCNHQ SCMDDPHIWG VLKFRQLWNL NKMRWTPTAS DICFTREFHS SFFSRGKCVP
     VVRGDGVYQK GMDFLLERLN QGEWIHIFPE GRVNMSGEFM RIKWGIGRLI AECSLHPIIL
     PMWHIGMNDV LPNETPYIPR VGQRITVLVG KPFTVRHLVN ALRAENTNPT EMRKTVTDYI
     QDEFRSLKAQ AEALHHRLQN HT
//
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