ID F1QHJ5_DANRE Unreviewed; 607 AA.
AC F1QHJ5; A0A8M3AMF1;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 2.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Clathrin interactor 1-like isoform X2 {ECO:0000313|RefSeq:XP_009293877.1};
DE SubName: Full=Clathrin interactor 1b {ECO:0000313|Ensembl:ENSDARP00000111775};
GN Name=clint1b {ECO:0000313|Ensembl:ENSDARP00000111775,
GN ECO:0000313|RefSeq:XP_009293877.1,
GN ECO:0000313|ZFIN:ZDB-GENE-111011-3};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000111775};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000111775}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000111775};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000111775, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000111775,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:XP_009293877.1}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_009293877.1};
RG RefSeq;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; CABZ01062489; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01062490; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01062491; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01062492; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01062493; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01062494; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01062495; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_009293877.1; XM_009295602.3.
DR STRING; 7955.ENSDARP00000111775; -.
DR PaxDb; 7955-ENSDARP00000111775; -.
DR Ensembl; ENSDART00000125658; ENSDARP00000111775; ENSDARG00000089914.
DR Ensembl; ENSDART00000125658.3; ENSDARP00000111775.2; ENSDARG00000089914.3.
DR GeneID; 100537648; -.
DR AGR; ZFIN:ZDB-GENE-111011-3; -.
DR CTD; 100537648; -.
DR ZFIN; ZDB-GENE-111011-3; clint1b.
DR eggNOG; KOG2057; Eukaryota.
DR HOGENOM; CLU_032178_1_0_1; -.
DR OMA; AMPTMPH; -.
DR OrthoDB; 1532at2759; -.
DR TreeFam; TF313361; -.
DR Reactome; R-DRE-432722; Golgi Associated Vesicle Biogenesis.
DR Proteomes; UP000000437; Chromosome 21.
DR Bgee; ENSDARG00000089914; Expressed in retina and 19 other cell types or tissues.
DR GO; GO:0030125; C:clathrin vesicle coat; IBA:GO_Central.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0030276; F:clathrin binding; IBA:GO_Central.
DR GO; GO:0005543; F:phospholipid binding; IBA:GO_Central.
DR GO; GO:0006897; P:endocytosis; IBA:GO_Central.
DR CDD; cd16989; ENTH_EpsinR; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR12276:SF45; ENTHOPROTIN-RELATED; 1.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT DOMAIN 1..131
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 253..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 65836 MW; C1A3687B10B62525 CRC64;
MNYSEIESKV REATNDDPWG PSGQLMGEIA KSTFMYEQFP EVMNMLWTRM LKDNKKNWRR
VYKALLLLAY LIRNGSERVV TSAREHIYDL RSLENYHFVD ENGKDQGINV RQKVKEMVEF
VQDDDRLREE RKKAKKNKDK YIGVSSDNMG SSRQSNSGER FDAESKSKWD EDWDKNKSSF
PFSEKLGEIG DKIGSTIDDT ISKFRKKEKD DSPDHISDNE EDRVSQNGRP AKLEFKDDEE
IITTNSIQIT QSTDTITSNS TTTTLTRKRG GVPSKTVDLG AAAHYTGDNS SPEADNKTSA
NQSSTPGLTD LLIVQSGSGH LLSSGRNSNL ISDFADFSSP AASASLPPAS VLLSAGNGEF
CGWNTVSTTP PDATTQSPIP DLFSDMSVPT ASTPTSALLS SADLFDLMAP NNSSISTSQS
MTFNMCPQNA TSALSRSQTI GSQLLPQQMG LQTSEGKLSM PSTWSDPSVN ISLDFLSAGL
NPSKPTQPTL NTMMQQGVQP PLQMVTHNFA RMTLNAQSST AAPKRGMNPM MVGVTPPTMA
MGTTGIGSVG IGSMSVNQGL VGTNIVPAKI GLQGALGMPS MGTGQGMNPS MVQPKQDAFA
SFGYFGK
//
