ID F1RIJ6_PIG Unreviewed; 711 AA.
AC F1RIJ6;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 5.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Zinc finger and BTB domain containing 48 {ECO:0000313|Ensembl:ENSSSCP00000003668.5};
GN Name=ZBTB48 {ECO:0000313|Ensembl:ENSSSCP00000003668.5,
GN ECO:0000313|VGNC:VGNC:98738};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000003668.5, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000003668.5, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000003668.5,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000003668.5}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F1RIJ6; -.
DR STRING; 9823.ENSSSCP00000003668; -.
DR Ensembl; ENSSSCT00000003754.5; ENSSSCP00000003668.5; ENSSSCG00000003383.5.
DR VGNC; VGNC:98738; ZBTB48.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000158981; -.
DR HOGENOM; CLU_002678_70_0_1; -.
DR InParanoid; F1RIJ6; -.
DR TreeFam; TF331310; -.
DR Proteomes; UP000008227; Chromosome 6.
DR Bgee; ENSSSCG00000003383; Expressed in longissimus lumborum muscle and 41 other cell types or tissues.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0003691; F:double-stranded telomeric DNA binding; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR GO; GO:0010833; P:telomere maintenance via telomere lengthening; IEA:Ensembl.
DR CDD; cd18232; BTB_POZ_ZBTB48_TZAP_KR3; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24384:SF189; DEFORMED WINGS-RELATED; 1.
DR PANTHER; PTHR24384; FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00096; zf-C2H2; 6.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 11.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 9.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 11.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 26..89
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 293..320
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 321..348
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 352..379
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 380..408
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 409..437
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 438..466
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 467..494
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 495..522
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 523..551
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 552..579
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 580..607
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 161..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 669..711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 671..686
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 711 AA; 80543 MW; D66F6C11B6AEF189 CRC64;
MDGSFVQHSV RVLQELNKQR ERGQYCDATL DVGGLVFKAH WSVLACCSHF FQSLYGDGSG
GSVVLPAGFA EIFGLLLDFF YTGHLALTSG NRDQVLLAAR ELRVPEAVEL CQSFKPKTSV
GQVPSGQSGL GKAGPRDVNS HLKEPAGLEE EDVSRTLGQV PRDQELSGSP SPQRPQLGLP
AQSENPSFLR GKLKQALKLH PSEDKEPEDC KVPPRPFEAE GVQLQGGSNE WEVVVQVEDD
GDGDYVSETE TEAVPTRRKS NVVRKPCAAE PALSTGSLAA EPAEDRKGTA VPVECPTCHK
KFLSKYYLKV HNRKHTGEKP FECPKCGKCY FRKENLLEHE ARNCMNRSEQ VFTCSVCQET
FRRRMELRVH AVSHTGEMPY KCSSCAQQFM QKKDLQSHMI KLHGAPKPHA CPTCAKCFLS
RTELQLHEAF KHRGEKLFVC EECGHRASSR NGLQMHIKAK HRNERPYVCE FCSHAFTQKA
NLNMHLRTHT GEKPFQCHLC GKTFRTQASL DKHNRTHTGE RPFSCEFCEQ RFTEKGPLLR
HVASRHQEGR PHFCQICGKT FKAVEQLRVH VRRHKGVRKF ECTECGYKFT RQAHLRRHME
IHDRVENYNP RQRKLRNLVI EDEKMVVVAL QPPASWRWAQ PRSSWSHWPR AAWPPSSLAR
DCVRRRASQA RASWSPRSSS RPPSPRTVTH SPLPASARWA PVPNKPRDFG L
//
