ID F1RQF2_PIG Unreviewed; 763 AA.
AC F1RQF2;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=SRY-box transcription factor 30 {ECO:0000313|Ensembl:ENSSSCP00000018064.3};
GN Name=SOX30 {ECO:0000313|Ensembl:ENSSSCP00000018064.3,
GN ECO:0000313|VGNC:VGNC:93356};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000018064.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000018064.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000018064.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000018064.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_003134153.1; XM_003134105.4.
DR AlphaFoldDB; F1RQF2; -.
DR SMR; F1RQF2; -.
DR STRING; 9823.ENSSSCP00000018064; -.
DR PaxDb; 9823-ENSSSCP00000018064; -.
DR Ensembl; ENSSSCT00000018564.5; ENSSSCP00000018064.3; ENSSSCG00000017051.5.
DR GeneID; 100521345; -.
DR KEGG; ssc:100521345; -.
DR CTD; 11063; -.
DR VGNC; VGNC:93356; SOX30.
DR eggNOG; KOG0527; Eukaryota.
DR GeneTree; ENSGT00940000161042; -.
DR HOGENOM; CLU_021249_0_0_1; -.
DR InParanoid; F1RQF2; -.
DR OMA; FIPSPAY; -.
DR OrthoDB; 2902801at2759; -.
DR TreeFam; TF336594; -.
DR Proteomes; UP000008227; Chromosome 16.
DR Bgee; ENSSSCG00000017051; Expressed in testis and 3 other cell types or tissues.
DR GO; GO:0010369; C:chromocenter; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008013; F:beta-catenin binding; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:1990837; F:sequence-specific double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:Ensembl.
DR GO; GO:0120211; P:proacrosomal vesicle fusion; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0031960; P:response to corticosteroid; IEA:Ensembl.
DR CDD; cd22033; HMG-box_SoxH_SOX30; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR47279; TRANSCRIPTION FACTOR SOX-30; 1.
DR PANTHER; PTHR47279:SF1; TRANSCRIPTION FACTOR SOX-30; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 348..416
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 348..416
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 123..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 689..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 735..763
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..33
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 763 AA; 83252 MW; 7B9DF0CDFA05025C CRC64;
MERARPEPPP QPRQLPRVTP PRPLRPAPPP LPVEGVSFRA AAVEPSPSPP APCAAAIATV
ASSYGEAPAS SVQPAARRLL QVKPEQVLLL PPGPPLPQTR EEGAAASPAQ ARLLQLRPEL
LLLPPPLPAS EGAPSRPELQ PRTLHVKAEK QELGPGLDPS VGPRRVFEAG PKVSRATKVE
GPGPDLDSSR GEEKGKLEAE EVMSYTLKGG EGKSLAALRE GVIKTEEPER LRDDCRLGTE
SASNGLVHGS KDVILTQPSS AFGPHQQDLR IPLTLHTVPP GARIQFQGPP PSELIRLTKV
PLTPVPIKMQ SLLEPSVKIE TKDVPLTVLP SDAGIPDTPF SKDRNGHVKR PMNAFMVWAR
IHRPALAKAN PAANNAEISV QLGLEWNKLS EEQKKPYYDE AQKIKEKHRE EFPGWVYQPR
PGKRKRFPLS VSNVFSGTTQ NIISTNPTTI YPYRSPTYSV VIPSLQNTIT HPVGEAPPAI
QLPTPAVQRP SPITLFQPSV STAQVAVQAP SLPLRPALPP QRFAGPSQTD THRLHSGASC
SVKRPTPVSP ESTSRIPTSA STAHARFASS TIQPPKEYPS VSTCPRSAPI PQPPPIPHSH
VYQPPPLGHP ATLFGTPPRF SFHHPYFLPG PHYFPSSTCP YSRPPFGYGN FPSSMPECLG
YYEDRYQKHE AMFSALNRDY PFRDYPDERA HSEDSRSCES MDGTSYYNSH SHSGEEYLNP
MPQLDIGALE NVFTAPTSTP SSIQQVNVTD SDEEEEEKVL RNL
//
