ID F1RR95_PIG Unreviewed; 378 AA.
AC F1RR95;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Forkhead box I1 {ECO:0000313|Ensembl:ENSSSCP00000018021.2};
DE SubName: Full=Forkhead box protein I1 isoform a {ECO:0000313|EMBL:HDB24793.1};
GN Name=FOXI1 {ECO:0000313|Ensembl:ENSSSCP00000018021.2,
GN ECO:0000313|VGNC:VGNC:88208};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000018021.2, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000018021.2, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000018021.2,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:HDB24793.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000018021.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; DQIR01169316; HDB24793.1; -; Transcribed_RNA.
DR RefSeq; XP_003134114.1; XM_003134066.4.
DR STRING; 9823.ENSSSCP00000018021; -.
DR PaxDb; 9823-ENSSSCP00000018021; -.
DR Ensembl; ENSSSCT00000018521.4; ENSSSCP00000018021.2; ENSSSCG00000017009.4.
DR GeneID; 100511481; -.
DR KEGG; ssc:100511481; -.
DR CTD; 2299; -.
DR VGNC; VGNC:88208; FOXI1.
DR eggNOG; KOG2294; Eukaryota.
DR GeneTree; ENSGT00940000161316; -.
DR HOGENOM; CLU_046860_1_0_1; -.
DR OMA; TGIIYHR; -.
DR OrthoDB; 5385885at2759; -.
DR TreeFam; TF316127; -.
DR Proteomes; UP000008227; Chromosome 16.
DR Bgee; ENSSSCG00000017009; Expressed in adult mammalian kidney and 5 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd20053; FH_FOXI1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF180; FORKHEAD BOX PROTEIN I1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 124..218
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 124..218
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 378 AA; 40249 MW; 53E71AC0CFD6A3FC CRC64;
MSSFDLPAPS PPRCSPQFPS IGQEPPEMNL YYENFFHAQG VPSPQRPPSF EGGGEFGATP
NPYLWLNGPA MTPPPYLPGT SASPFLPQTY GVQRQLLPGV SGLGGGDLGW LPIPSQEELM
KLVRPPYSYS ALIAMAIHGA PDKRLTLSQI YQYVADNFPF YNKSKAGWQN SIRHNLSLND
CFKKVPRDED DPGKGNYWTL DPNCEKMFDN GNFRRKRKRK SDVSSSTGSL ASEKTETSLL
GGSAKAAEAQ DLLDGASPGP GGSPEKRASP PPPATPCLNG FLSTVSAYVS GSGPGSRPVA
TPGLSPEPAD KLAQNLLNFN SYTTLGNISG HAGGGEWAPP APGSTLGYGG AALNQFSPHF
YNGINTNGIL YPREGSEV
//
