ID   F1RW85_PIG              Unreviewed;       767 AA.
AC   F1RW85;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2019, sequence version 4.
DT   27-MAR-2024, entry version 66.
DE   SubName: Full=Family with sequence similarity 171 member A1 {ECO:0000313|Ensembl:ENSSSCP00000011783.4};
GN   Name=FAM171A1 {ECO:0000313|Ensembl:ENSSSCP00000011783.4,
GN   ECO:0000313|VGNC:VGNC:96011};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000011783.4, ECO:0000313|Proteomes:UP000008227};
RN   [1] {ECO:0000313|Ensembl:ENSSSCP00000011783.4, ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000011783.4,
RC   ECO:0000313|Proteomes:UP000008227};
RG   Porcine genome sequencing project;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSSCP00000011783.4}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC   -!- SIMILARITY: Belongs to the FAM171 family.
CC       {ECO:0000256|ARBA:ARBA00006818}.
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DR   AlphaFoldDB; F1RW85; -.
DR   PeptideAtlas; F1RW85; -.
DR   Ensembl; ENSSSCT00000012091.5; ENSSSCP00000011783.4; ENSSSCG00000011047.5.
DR   VGNC; VGNC:96011; FAM171A1.
DR   eggNOG; ENOG502QR89; Eukaryota.
DR   GeneTree; ENSGT00950000183184; -.
DR   HOGENOM; CLU_019729_0_0_1; -.
DR   TreeFam; TF331338; -.
DR   Proteomes; UP000008227; Chromosome 10.
DR   Bgee; ENSSSCG00000011047; Expressed in endocardial endothelium and 42 other cell types or tissues.
DR   ExpressionAtlas; F1RW85; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018890; FAM171.
DR   InterPro; IPR049175; FAM171_C.
DR   InterPro; IPR048530; FAM171_N.
DR   PANTHER; PTHR31626:SF1; PROTEIN FAM171A1; 1.
DR   PANTHER; PTHR31626; SUSHI DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF20771; FAM171A1-2-B_C; 1.
DR   Pfam; PF10577; FAM171A1-2-B_N; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..767
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5023882747"
FT   DOMAIN          34..198
FT                   /note="FAM171 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10577"
FT   DOMAIN          266..765
FT                   /note="FAM171 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF20771"
FT   REGION          189..227
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          297..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          604..654
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          692..767
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..311
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        699..715
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        747..767
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   767 AA;  84055 MW;  C6DD0FD96E4CA2AD CRC64;
     MSRSTALLLC LLGCNVWKAV TKTLREPGAG AQEVTLKVHI SDASTHQPIP EALIEIFTNQ
     VSIATGTSGT DGVAFIKFQY KLGSQLMVTA TKHAYVPNSA PWKPIRLPVF SSLSLGLLPE
     RSATLMVYED VVQIVSGFQG ARPQPRVHFQ RRALRLPENT SYSDLTAFLT AASSPSEVDG
     FPYLRGLDGN GTGNGTRRKC LKPRQHHRKL QLPATLESSK KDQSTSMSHI NLLFSRRESE
     FPGPLSVTSQ GRPPDAPGSK ELMSGVHLEM VSSNGEADLH TPMLKLSYST SQEFSSREEL
     LSHKEEDKSQ ISFDNLTPSG TLGKDYHKSV EIFPLKSRKS LEREGCESPG STDYRRSYNA
     MLSQPLFEKQ DRDGQAPINH ISAGSKLAIQ EHMYPTPSSP EKEQLLERRP TECMMSRSVD
     HLERPTSFPR PGQLICCSSV DQVNDSVYRK VLPALVIPAH YMKLPGDHSY VGQPLVVPAD
     QQLEIERLQA ELSSPHAGIF PHPSSQIQAQ PLSCQAISQQ HLQDAGTREW TPQSAAMSES
     LSIPASLNDA ALAQMNSEVQ LLTEKALLEL GGGKPLPHPR AWFVSLDGRS NAHVRHSYID
     LQRAGRNGSN DASLDSGVDM NEPKSARKAR GDPLSLPQNH PPVQEHPQKE PRAADGGAAY
     TQLVYLEDLD QSSGGEGGPA VGTPEDSALR CLLDGSSRRS GGQLPSLQEE TTKRTSGVPP
     EPPASPDPKR SAQEDEEDED DDDDQGEDKK SPWQKREERP LMAFNIK
//