ID F1S1C6_PIG Unreviewed; 425 AA.
AC F1S1C6;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 4.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Fc receptor like B {ECO:0000313|Ensembl:ENSSSCP00000006767.4};
GN Name=FCRLB {ECO:0000313|Ensembl:ENSSSCP00000006767.4,
GN ECO:0000313|VGNC:VGNC:88074};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000006767.4, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000006767.4, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000006767.4,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000006767.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_001925993.1; XM_001925958.2.
DR AlphaFoldDB; F1S1C6; -.
DR SMR; F1S1C6; -.
DR PaxDb; 9823-ENSSSCP00000006767; -.
DR Ensembl; ENSSSCT00000006956.5; ENSSSCP00000006767.4; ENSSSCG00000006348.6.
DR VGNC; VGNC:88074; FCRLB.
DR eggNOG; ENOG502SH8W; Eukaryota.
DR GeneTree; ENSGT01050000244808; -.
DR InParanoid; F1S1C6; -.
DR TreeFam; TF351107; -.
DR Proteomes; UP000008227; Chromosome 4.
DR Bgee; ENSSSCG00000006348; Expressed in blood.
DR ExpressionAtlas; F1S1C6; baseline.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IBA:GO_Central.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0050777; P:negative regulation of immune response; IBA:GO_Central.
DR CDD; cd05753; Ig2_FcgammaR_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR PANTHER; PTHR11481:SF114; FC RECEPTOR-LIKE B; 1.
DR PANTHER; PTHR11481; IMMUNOGLOBULIN FC RECEPTOR; 1.
DR Pfam; PF13895; Ig_2; 2.
DR SMART; SM00409; IG; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..425
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023928042"
FT DOMAIN 23..101
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 318..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 402..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 425 AA; 47146 MW; F08CB8193DBC0771 CRC64;
MWSLAAFLLL VPSIGQAATL EKPILSLHPP WTTIFKGERV TLRCDGYHPL LLELRPISTL
WYLGHLLLPS HKKSIEVQTP GIYRCQTRGA PVSDPIHLSV SNDWLILQVP YAVVFEGEPL
VMRCRGWYDK VVYKLHYYQD DQPVRYFHSS ANYTVPQARA SDSGRYQCSG TMRIPVESAP
MFSAKVAVTV QELFQAPVLR VMGRVQGRGP ALGGVVLRCE THLHPQKRDT PLQFAFYKYS
RPVRRFDWGT EYMVPEPEVE ELETYWCEAA TATRSVRKRS PWLQLPGPGS PLDLASTTAP
VPKAAALAPA NKPLSFRKPP VSRSVPAVTS VPNTTSAGLQ FPSGRGPTAE PPACAPPTPL
EQTAGALKPD VDLLLREMQL LKGLLSRVVL ELKEPKAFPE HRETLETTSH FAVSQGTPET
TAVES
//
