ID F1S285_PIG Unreviewed; 1760 AA.
AC F1S285;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 3.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Collagen type XIV alpha 1 chain {ECO:0000313|Ensembl:ENSSSCP00000006405.3};
GN Name=COL14A1 {ECO:0000313|Ensembl:ENSSSCP00000006405.3,
GN ECO:0000313|VGNC:VGNC:97936};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000006405.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000006405.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000006405.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000006405.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR PeptideAtlas; F1S285; -.
DR Ensembl; ENSSSCT00000006580.5; ENSSSCP00000006405.3; ENSSSCG00000005997.6.
DR VGNC; VGNC:97936; COL14A1.
DR GeneTree; ENSGT00940000153769; -.
DR HOGENOM; CLU_002527_2_0_1; -.
DR OMA; REMQSDX; -.
DR TreeFam; TF329914; -.
DR ChiTaRS; COL14A1; pig.
DR Proteomes; UP000008227; Chromosome 4.
DR Bgee; ENSSSCG00000005997; Expressed in ovary and 40 other cell types or tissues.
DR ExpressionAtlas; F1S285; baseline and differential.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 7.
DR CDD; cd01482; vWA_collagen_alphaI-XII-like; 2.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF15; COLLAGEN ALPHA-1(XIV) CHAIN; 1.
DR Pfam; PF01391; Collagen; 4.
DR Pfam; PF00041; fn3; 8.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00060; FN3; 8.
DR SMART; SM00210; TSPN; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 7.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS50853; FN3; 7.
DR PROSITE; PS50234; VWFA; 2.
PE 1: Evidence at protein level;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F1S285};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 32..123
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 158..330
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 355..444
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 445..536
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 537..626
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 627..716
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 717..810
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 811..901
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1012..1185
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 126..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1442..1591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1626..1760
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1541..1555
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1638..1655
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1690..1727
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1760 AA; 189820 MW; 68FD7CABBE22A6FB CRC64;
MKIFQCKMQY WLFPAFLAVT YFCTIVQGQV APPTRLRYNV LSHDSIQISW KAPRGKFGGY
KLLVTPAAGG KTNQLNLQNT ATKAIIQGLM PDQNYTVQII AYHKDKESKP AQGQFRIKDI
EKRKEPKPRV KVVDRDGNKP STPEEEVKFF CQTPAIADIV ILVDGSWSIG RFNFRLVRSF
LENLVTAFNV GSEKTRIGLA QYSGDPRIEW HLNAFSTKDE VIEAVRNLPY KGGNTLTGLA
LNYIFENSFK PEAGARTGVS KIGILITDGK SQDDVIPPSR NLRESGVELF AIGVKNADEN
ELREIASEPD NTHVYNVAEF DLMHTVVESL TRTVCSRVEE QDREIKASAL AAIGPPTELL
TSEVTARSFM VNWTHAPGKV EKYRVVYYPT RGGKPEEVVV DGSISSTVLK NLMSLTEYQI
AVFAIYAHTA SEGLRGTETT LALPIASDLE LYDVTENSLR ARWNPVAGAS GYLILYAPLT
EGLAGDEKEM KIGETHTDIE LRGLLPNTEY TVTVYAMFGE EASDPVTGQE TTLPLSPPRN
LRISNVGSNS ARLAWDPTSR RISGYRIVYN NADGTEINEV EVDPITTFPL KGLTPITEYT
VAIFSIYDEG QSEPLTGIFS TEEVPAQQYL EIDEVMTDSF RVTWHPLSAD EGQHKLMWIP
VYGGKTQEVV LKEDQDSYVI EGLEPGTEYE VSLLAVLDDG SESEVVTAVG TTLFRTGIRN
LVVDDETTSS LRVKWDISDS SVQQFRVTYL TAQGDPAEEV VGTVMVSGNQ NDLLLKNLLS
NTEYKVTVTP IYDDGEGVSV SAPGKTLPPS GPQNLRVSEE WYNRLRITWD PPSSPVKGYR
IVYKPVSVAG PTLETFVGAN INTILITNLL SGMDYNVKIF ASQASGFSDA LTGVVKTLFL
GVTDLQADQI QMTSLCARWQ VQRHATAYRI VIESLQDTQK QESTLGGGTT RHCFYGLQPD
SQYKISVYTK LQEMEGPSVS IMEKTKSLPT PPPTFPPTIP PAKEVCKAAK ADLVFMVDGS
WSIGDENFNK ITNFLYSTVG ALDKIGADGT QVAMVQFTDD PRTEFKLNTY KTKETLLDAI
KHISYKGGNT KTGKAIKHVR DNLFTAESGI RRGIPKVIVV ITDGRSQDDV NKISKEMQLD
GYSIFAVGVA DADYSELVSI GSKPSARHVF FVDDFDAFKK IEDELITFVC ETASATCPLV
HKDGIDLAGF KMMELFGLVE KDFSSVEGVS MEPGTFNVYP CYHLHKDALV SQPTKYLHPE
GLPSDYTISF LFRVLPDTPE EPFALWEILN KNSDPLVGVI LDNGGKTLTY FNYDYSGDFQ
TVTFEGPEIR KIFYGSFHKL HIIVSKTMAK VVIDCKEVGE KAINASSNIT SDGVEVLGRM
VRSRGPNGNS APFQLQMFDI VCSTSWANKD KCCELPGLRD EETCPELPHS CSCSEINKGA
LGPAGPPGGP GLRGPKGQRG EPGPKGPDGP RGETGPPGHQ GPPGPQGPSG LSIQGMPGMP
GEKGEKGETG LPGPQGIPGS VGSPGRDGSP GQRGFPGKDG SSGPPGPPGP IGIPGAPGVP
GITGSMGPQG ALGPPGAPGA KGERGERGDL QSQAMVRAVA RQVCEQLIQS HMARYTAILN
QIPSHSSSIR TIQGPPGEPG RPGSPGAPGE QGPPGSPGFP GNAGVPGTPG ERGLTGVKGE
KGNPGIGTQG PRGPPGPAGP SGESRPGSPG PPGSPGPRGP PGHLGVPGPQ GPSGQPGYCD
PSSCSAYGVG DLIPYNDYQH
//
