ID F1S657_PIG Unreviewed; 366 AA.
AC F1S657;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 {ECO:0000313|Ensembl:ENSSSCP00000016497.1};
DE SubName: Full=Putative C->U-editing enzyme APOBEC-4 {ECO:0000313|EMBL:HCZ83910.1};
GN Name=APOBEC4 {ECO:0000313|Ensembl:ENSSSCP00000016497.1,
GN ECO:0000313|VGNC:VGNC:85419};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000016497.1, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000016497.1, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000016497.1,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:HCZ83910.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000016497.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; DQIR01028435; HCZ83910.1; -; Transcribed_RNA.
DR RefSeq; XP_003130417.1; XM_003130369.3.
DR STRING; 9823.ENSSSCP00000016497; -.
DR PaxDb; 9823-ENSSSCP00000016497; -.
DR Ensembl; ENSSSCT00000016951.4; ENSSSCP00000016497.1; ENSSSCG00000015561.4.
DR GeneID; 100515680; -.
DR KEGG; ssc:100515680; -.
DR CTD; 403314; -.
DR VGNC; VGNC:85419; APOBEC4.
DR eggNOG; ENOG502QQXT; Eukaryota.
DR GeneTree; ENSGT00390000014243; -.
DR HOGENOM; CLU_832944_0_0_1; -.
DR OMA; HNAYEIN; -.
DR OrthoDB; 68574at2759; -.
DR TreeFam; TF338173; -.
DR Reactome; R-SSC-72200; mRNA Editing: C to U Conversion.
DR Reactome; R-SSC-75094; Formation of the Editosome.
DR Proteomes; UP000008227; Chromosome 9.
DR Bgee; ENSSSCG00000015561; Expressed in lung and 6 other cell types or tissues.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR InterPro; IPR038953; APOBEC4.
DR InterPro; IPR002125; CMP_dCMP_dom.
DR PANTHER; PTHR35672; C-U-EDITING ENZYME APOBEC-4-RELATED; 1.
DR PANTHER; PTHR35672:SF1; C-U-EDITING ENZYME APOBEC-4-RELATED; 1.
DR Pfam; PF18778; NAD1; 1.
DR PROSITE; PS51747; CYT_DCMP_DEAMINASES_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 61..177
FT /note="CMP/dCMP-type deaminase"
FT /evidence="ECO:0000259|PROSITE:PS51747"
FT REGION 327..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 366 AA; 41611 MW; C4E888720AE9B6FB CRC64;
MEPLYEEYLA NCGTIVKPYY WLSFSLDCSN CPYHIRTGEE ARVPYTEFYQ LFGFPYGPTG
PQTKHLAFYE LRPSSGSLVQ KGHASSCTGN DTHPESMLFE RNGYFDSAIR NNNGIRHIIL
YSNNSPCNEA NHCCISKMYN FLRMYPDVTL SIYFSQLYHT EAEFPASAWN REALRSLASL
WPQVTLSPIS GGIWHSLLHN FVSGVSGWPL FQPILTGRAL ADRHNAYEIN AITGVKPNFT
DVLPQVKENQ NIKTQAALEA YPLNNVFPRQ SFQMTSGQLQ PNLTLDPRVP VVFVLVPFRE
LPPIYVRQNP HKPRNIVRHF NLPQMSFQET NDLRRPPRGG PAESAEITEQ FASSKVADEK
KKTGKK
//
