ID F1SBJ2_PIG Unreviewed; 858 AA.
AC F1SBJ2;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=ESF1 nucleolar pre-rRNA processing protein homolog {ECO:0000313|Ensembl:ENSSSCP00000007539.2};
GN Name=ESF1 {ECO:0000313|Ensembl:ENSSSCP00000007539.2,
GN ECO:0000313|VGNC:VGNC:95697};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000007539.2, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000007539.2, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000007539.2,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000007539.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the ESF1 family.
CC {ECO:0000256|ARBA:ARBA00009087}.
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DR RefSeq; XP_001926103.3; XM_001926068.5.
DR AlphaFoldDB; F1SBJ2; -.
DR STRING; 9823.ENSSSCP00000007539; -.
DR PaxDb; 9823-ENSSSCP00000007539; -.
DR Ensembl; ENSSSCT00000007748.4; ENSSSCP00000007539.2; ENSSSCG00000007077.4.
DR GeneID; 100155396; -.
DR KEGG; ssc:100155396; -.
DR CTD; 51575; -.
DR VGNC; VGNC:95697; ESF1.
DR eggNOG; KOG2318; Eukaryota.
DR GeneTree; ENSGT00390000004881; -.
DR HOGENOM; CLU_010564_2_1_1; -.
DR InParanoid; F1SBJ2; -.
DR OMA; YEMEMSW; -.
DR OrthoDB; 131620at2759; -.
DR TreeFam; TF105822; -.
DR Proteomes; UP000008227; Chromosome 17.
DR Bgee; ENSSSCG00000007077; Expressed in hindlimb bud and 47 other cell types or tissues.
DR ExpressionAtlas; F1SBJ2; baseline and differential.
DR Genevisible; F1SBJ2; SS.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR039754; Esf1.
DR InterPro; IPR012580; NUC153.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR PANTHER; PTHR12202:SF0; ESF1 HOMOLOG; 1.
DR PANTHER; PTHR12202; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 766..794
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 77..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 547..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 645..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 688..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 801..836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..303
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..565
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..581
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..828
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 858 AA; 99404 MW; EE8FD64C61B5F27A CRC64;
MASKQEIMND QRFRRVTKDP RFWEMPEKER KVKIDKRFRA MFHDKKFKLN YAVDKRGRPI
NHSTTEDLKR FYELSDSDSD LSDENNKVLS QKKIKKKKNQ TKSEVETKNF VEKKKETKKI
NQKDFGNKND LDNSERIQEK KTPCKSNKMD SISPKKNSKK FTQKSTKGEK NIVQHSTDSF
TKGKLRTVGS GTAEIVPSPK VKYSKTKREM QSVVPCIMAR DSDGPENSTD GEVFDQDALE
EDSESASEIG DEESEDESTG IDGADVDGDD DDDDGNENEE EEDEDEDSED EDEGSEEEDE
SDSGPDLARG KGNIETSSED EEDMADLLPE ESGFEHAWRE LDKDAPRADE ITRRLAVCNM
DWDRLKAKDL LALFNSFKPK GGVVFSVKIY PSEFGKQRMQ EEQVQGPVEL LSIPEDAPEK
DWTSREKLRD YQFKRLKYYY AVVDCDSPET AAKIYEDCDG LEFESSCSFI DLRFIPDDIT
FDDEPKDVAS EVDLTAYKPK YFTSAAMGTS TVEITWDETD HERITTLNRK FKKEELLDMD
FQAYLASSSE DEEEIEEELQ GDDEVNVEED GKTKRTQKDD EEQIAKYRQL LQVIQEKEKK
GKENDMEMEI KWVPGLKESA EEMVKNKLEG KDKLTPWEQF LEKKKEKKRL KKKQKALAAE
ASEDEVPSDI DLNDPYFAEE AKKIGIKEKK KSMKSAKDGT SPEEEAEIER QKAEMALLVM
DEEEESKKHF NYNKIVEHQN LSKKKKKQLM KKKELLEDDF EVNVKDTRFQ AMYTSHLFNL
DPSDPNFKKT KAMEKILEEK ARQREQKEQE LTQATKKKES EIQKESQKKS IDPALSMLIK
SVKNKTEQFQ ARKKQKVK
//
