ID F1SDT5_PIG Unreviewed; 446 AA.
AC F1SDT5; A0A4X1TU87;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 3.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Intraflagellar transport 52 {ECO:0000313|Ensembl:ENSSSCP00000007845.3};
DE SubName: Full=Intraflagellar transport protein 52 homolog isoform X1 {ECO:0000313|EMBL:HDB68704.1};
GN Name=IFT52 {ECO:0000313|Ensembl:ENSSSCP00000007845.3,
GN ECO:0000313|VGNC:VGNC:95699};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000007845.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000007845.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000007845.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:HDB68704.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000007845.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; DQIR01213227; HDB68704.1; -; Transcribed_RNA.
DR EMBL; DQIR01223151; HDB78628.1; -; Transcribed_RNA.
DR EMBL; DQIR01290596; HDC46074.1; -; Transcribed_RNA.
DR EMBL; DQIR01296082; HDC51560.1; -; Transcribed_RNA.
DR RefSeq; XP_005657724.1; XM_005657667.2.
DR PaxDb; 9823-ENSSSCP00000007845; -.
DR Ensembl; ENSSSCT00000008060.5; ENSSSCP00000007845.3; ENSSSCG00000007364.5.
DR Ensembl; ENSSSCT00005066063.1; ENSSSCP00005040901.1; ENSSSCG00005041168.1.
DR GeneID; 100157616; -.
DR KEGG; ssc:100157616; -.
DR CTD; 51098; -.
DR VGNC; VGNC:95699; IFT52.
DR eggNOG; KOG3861; Eukaryota.
DR GeneTree; ENSGT00390000011581; -.
DR OrthoDB; 149972at2759; -.
DR TreeFam; TF105916; -.
DR Proteomes; UP000008227; Chromosome 17.
DR Bgee; ENSSSCG00000007364; Expressed in pituitary gland and 43 other cell types or tissues.
DR GO; GO:0005814; C:centriole; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR GO; GO:0097546; C:ciliary base; IEA:Ensembl.
DR GO; GO:0097542; C:ciliary tip; IEA:Ensembl.
DR GO; GO:0044292; C:dendrite terminus; IEA:Ensembl.
DR GO; GO:0030992; C:intraciliary transport particle B; IEA:Ensembl.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR GO; GO:0032391; C:photoreceptor connecting cilium; IEA:Ensembl.
DR GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR GO; GO:0035720; P:intraciliary anterograde transport; IEA:Ensembl.
DR GO; GO:0043616; P:keratinocyte proliferation; IEA:Ensembl.
DR GO; GO:0010839; P:negative regulation of keratinocyte proliferation; IEA:Ensembl.
DR GO; GO:0001841; P:neural tube formation; IEA:Ensembl.
DR GO; GO:1905515; P:non-motile cilium assembly; IEA:Ensembl.
DR GO; GO:0070613; P:regulation of protein processing; IEA:Ensembl.
DR GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR Gene3D; 6.10.250.2800; -; 1.
DR InterPro; IPR019196; ABC_transp_unknown.
DR InterPro; IPR039975; IFT52.
DR InterPro; IPR048643; Itf52_C.
DR PANTHER; PTHR12969:SF7; INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG; 1.
DR PANTHER; PTHR12969; NGD5/OSM-6/IFT52; 1.
DR Pfam; PF09822; ABC_transp_aux; 1.
DR Pfam; PF21178; Itf52_C; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000313|EMBL:HDB68704.1};
KW Cilium {ECO:0000313|EMBL:HDB68704.1};
KW Flagellum {ECO:0000313|EMBL:HDB68704.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 28..125
FT /note="ABC-type uncharacterised transport system"
FT /evidence="ECO:0000259|Pfam:PF09822"
FT DOMAIN 369..420
FT /note="Intraflagellar transport protein 52 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21178"
SQ SEQUENCE 446 AA; 50371 MW; 4AACE73083B8E743 CRC64;
MVVTGPQAIM EKELRSTILF NAYKKEVFTT SNGYKSMQKK LRGNWKIQSL KDEITSEKLI
GVKLWITAGP REKFTAAEFE VLKKYLDGGG DILVMLGEGG ESRFDTNINF LLEEYGIMVN
NDAVVRNVYY KYFHPKEALV SDGVLNREIS RAAGKAVPGI IDEESSGNNA QALTFVYPFG
ATLNVMKPAV AVLSTGSVCF PLNRPILAFY HSKDQGGKLA VLGSCHMFSD QYLDKEENSK
IMDVVFQWLT AGDIQLNQID AEDPEISDYM MVPDTATLSE RLRVCLQEGD ENPRDFTTLF
DLSIYQLDTT SLPKVIKAHE QLNVKHEPLQ LIQPQFETPL PTLQPAVFPP SFRELPPPPL
ELFDLDETFS SEKARLAQIT NKCTEDDLEF YIRKCGDILG VTNKLPKDQQ DAKHILEHIF
FQVVEFKKLN QEHDIDTSET AFQSNF
//
