ID F1SIZ2_PIG Unreviewed; 359 AA.
AC F1SIZ2;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 4.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=POC1 centriolar protein homolog A {ECO:0000256|ARBA:ARBA00039725};
GN Name=POC1A {ECO:0000313|Ensembl:ENSSSCP00000012178.4,
GN ECO:0000313|VGNC:VGNC:91615};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000012178.4, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000012178.4, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000012178.4,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000012178.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body
CC {ECO:0000256|ARBA:ARBA00004120}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriole
CC {ECO:0000256|ARBA:ARBA00004114}.
CC -!- SIMILARITY: Belongs to the WD repeat POC1 family.
CC {ECO:0000256|ARBA:ARBA00037984}.
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DR AlphaFoldDB; F1SIZ2; -.
DR Ensembl; ENSSSCT00000012506.4; ENSSSCP00000012178.4; ENSSSCG00000011426.5.
DR VGNC; VGNC:91615; POC1A.
DR eggNOG; ENOG502QSVJ; Eukaryota.
DR GeneTree; ENSGT00940000157494; -.
DR HOGENOM; CLU_000288_57_17_1; -.
DR TreeFam; TF324210; -.
DR Proteomes; UP000008227; Chromosome 13.
DR Bgee; ENSSSCG00000011426; Expressed in oocyte and 44 other cell types or tissues.
DR ExpressionAtlas; F1SIZ2; baseline and differential.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44019:SF2; POC1 CENTRIOLAR PROTEIN HOMOLOG A; 1.
DR PANTHER; PTHR44019; WD REPEAT-CONTAINING PROTEIN 55; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 7.
DR PROSITE; PS50294; WD_REPEATS_REGION; 7.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 15..56
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 57..88
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 99..140
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 141..182
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 183..224
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 225..266
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 267..299
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 359 AA; 40127 MW; 42E56F5F622B29A6 CRC64;
MASPYPEDPS LERHFKGHRD AVTCVDFSFN MKQLASGSMD SCLMVWHMKP QSRAYRFTGH
KDAVTCVNFS PSGHLLASGS RDKTVRIWVP NIKGESTVFR AHTATVRSVH FCSDGQSFVT
ASDDKTIKVW STHRQKFLFS LSQHINWVRC AKFSPDGRLI VSASDDKTVK LWDKTSRECV
HSYCEHGGFV TYVDFHPSGT CVAAAGMDNT VKVWDVRTHR LLQHYQLHSA AVNALSFHPS
GNYLVTASSD STLKILDLME GRLLYTLHGH QGPATTVAFS RTGEYFASGG SDEQVMVWKS
NFDVIDYGEV LRVQRPPATL ASSSGTLTVS ILEQRLTLTE DKLKQCLENQ QLIMQRTTP
//
