ID F1SKG5_PIG Unreviewed; 489 AA.
AC F1SKG5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 3.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|EMBL:HDB88623.1};
RN [1] {ECO:0000313|EMBL:HDB88623.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
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DR EMBL; DQIR01233146; HDB88623.1; -; Transcribed_RNA.
DR AlphaFoldDB; F1SKG5; -.
DR HOGENOM; CLU_009281_2_3_1; -.
DR OMA; ECCFEPG; -.
DR UniPathway; UPA00618; UER00672.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 3.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR PANTHER; PTHR10196:SF68; GLYCEROL KINASE 5-RELATED; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 2.
DR PIRSF; PIRSF000538; GlpK; 2.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:HDB88623.1};
KW Transferase {ECO:0000256|RuleBase:RU003733}.
FT DOMAIN 26..139
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 147..243
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 254..439
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 489 AA; 54171 MW; A56C690817E6092B CRC64;
MSELSTVAEQ ERQEQSAPDG RRAGFVLGLD VGSSVIRCHV YDRAARICGS SAQKVESLYP
QTGWVEIDPD VLWLQFVAVI KESVKAAGIE MNQIVGLGIS TQRGTFLTWD KKTGKHFHNF
ISWQDLRAVE LVKSWNSSLL MKVQKAIQEE NCCFGTVDTW LLHKLTKGSE FATDFSNAST
TGLFDPYEMC WSKLITSLLS IPLSLLPPVR DTSHNYGSVD EEIFGVPIPI VALVADQQSA
MFGECCFQTG DVKLTMGSGT FLDINTGNNP HQSVGGFYPL IGWKIGQEVV CLAEGNAGDT
GTAIQWAQKL GLFTDAAETE KMARSLEDSE VYFVPSFSGL QAPLNDPCAC ASFMGLKPST
TKYHLVRAIL ESIAFRNKQL YEVMQKEIHI PITKIRADGG VCKNSFVMQM TSDLINETID
RPVHVDMSCI GAASLAGLAV GFWTDKEELK KLRQSDIVFT PQKKCQEYEM SMGNWVKAVK
RSMNWYNKT
//
