GenomeNet

Database: UniProt
Entry: F2CR51_HORVV
LinkDB: F2CR51_HORVV
Original site: F2CR51_HORVV 
ID   F2CR51_HORVV            Unreviewed;       463 AA.
AC   F2CR51;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   05-JUN-2019, entry version 50.
DE   RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423};
DE            EC=2.3.1.- {ECO:0000256|RuleBase:RU003423};
OS   Hordeum vulgare subsp. vulgare (Domesticated barley).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX   NCBI_TaxID=112509 {ECO:0000313|EMBL:BAJ85322.1};
RN   [1] {ECO:0000313|EMBL:BAJ85322.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Shoot {ECO:0000313|EMBL:BAJ85322.1}, and Shoot and root
RC   {ECO:0000313|EMBL:BAJ94158.1};
RX   PubMed=21415278; DOI=10.1104/pp.110.171579;
RA   Matsumoto T., Tanaka T., Sakai H., Amano N., Kanamori H., Kurita K.,
RA   Kikuta A., Kamiya K., Yamamoto M., Ikawa H., Fujii N., Hori K.,
RA   Itoh T., Sato K.;
RT   "Comprehensive sequence analysis of 24,783 barley full-length cDNAs
RT   derived from 12 clone libraries.";
RL   Plant Physiol. 156:20-28(2011).
RN   [2] {ECO:0000313|EnsemblPlants:HORVU5Hr1G061140.1, ECO:0000313|Proteomes:UP000011116}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Morex {ECO:0000313|EnsemblPlants:HORVU5Hr1G061140.1}, and
RC   subsp. vulgare {ECO:0000313|Proteomes:UP000011116};
RX   PubMed=23075845; DOI=10.1038/nature11543;
RG   The International Barley Genome Sequencing Consortium;
RT   "A physical, genetic and functional sequence assembly of the barley
RT   genome.";
RL   Nature 491:711-716(2012).
RN   [3] {ECO:0000313|EnsemblPlants:HORVU5Hr1G061140.1}
RP   IDENTIFICATION.
RC   STRAIN=subsp. vulgare {ECO:0000313|EnsemblPlants:HORVU5Hr1G061140.1};
RG   EnsemblPlants;
RL   Submitted (OCT-2017) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|RuleBase:RU003423};
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003423}.
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DR   EMBL; AK354103; BAJ85322.1; -; mRNA.
DR   EMBL; AK362954; BAJ94158.1; -; mRNA.
DR   STRING; 4513.MLOC_63372.1; -.
DR   PRIDE; F2CR51; -.
DR   EnsemblPlants; HORVU5Hr1G061140.1; HORVU5Hr1G061140.1; HORVU5Hr1G061140.
DR   Gramene; HORVU5Hr1G061140.1; HORVU5Hr1G061140.1; HORVU5Hr1G061140.
DR   OMA; KSEMLVN; -.
DR   Proteomes; UP000011116; Unassembled WGS sequence.
DR   ExpressionAtlas; F2CR51; baseline and differential.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.559.10; -; 1.
DR   Gene3D; 4.10.320.10; -; 1.
DR   InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR036625; E3-bd_dom_sf.
DR   InterPro; IPR004167; PSBD.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   Pfam; PF02817; E3_binding; 1.
DR   SUPFAM; SSF47005; SSF47005; 1.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS00189; LIPOYL; 1.
DR   PROSITE; PS51826; PSBD; 1.
PE   2: Evidence at transcript level;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003423};
KW   Complete proteome {ECO:0000313|Proteomes:UP000011116};
KW   Lipoyl {ECO:0000256|RuleBase:RU003423};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011116};
KW   Transferase {ECO:0000256|RuleBase:RU003423}.
FT   DOMAIN       37    112       Lipoyl-binding. {ECO:0000259|PROSITE:
FT                                PS50968}.
FT   DOMAIN      163    200       Peripheral subunit-binding (PSBD).
FT                                {ECO:0000259|PROSITE:PS51826}.
FT   REGION      123    150       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F2CR51}.
FT   REGION      203    229       Disordered. {ECO:0000256|MobiDB-lite:
FT                                F2CR51}.
FT   COMPBIAS    205    224       Pro-rich. {ECO:0000256|MobiDB-lite:
FT                                F2CR51}.
SQ   SEQUENCE   463 AA;  48391 MW;  B84EE5F9610A19C2 CRC64;
     MASLASLSIY TVPRRAGRAD SVQTPRRRRM AVVRAKVREI FMPALSSTMT EGRIVSWTTA
     EGDRVSKGDP VVVVESDKAD MDVETFHDGI IAAVLVPAGG TAPVGAPIAL LAESEEDVAL
     AQARAQSLSK AQGEETPPPH AAATAPPTIA PAPAPVTAPT NGIATPHAKK LAKQHGVDIS
     NVVGTGPNGR ITAADVEAAA GIQPKPKAAP PPPPAAPPAP PAGTPSVGAV RQPAVLPPVP
     GATVVPFTSM QSAVSRNMVE SLSVPTFRVG YAIKTDKLDA LYEKVKLKGV TKTLLLVKAA
     GMALAQHPVV NASCRDGKSF SYNNSINVAV AVAIEGGLLT PVLEDVDKLD IYLLAQKWRA
     LLKKTRMKQL QPNEYNSGTF SLSNLGMFGV DRFDAILPPG QGAIMAVGAS RPTVIADKDG
     FFSIKNEMLV NVTADHRIIY GADLAAFLQT FAKIVEDPES LTL
//
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