ID F2D7W2_HORVV Unreviewed; 935 AA.
AC F2D7W2;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
OS Hordeum vulgare subsp. vulgare (Domesticated barley).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX NCBI_TaxID=112509 {ECO:0000313|EMBL:BAJ91183.1};
RN [1] {ECO:0000313|EMBL:BAJ91183.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Shoot {ECO:0000313|EMBL:BAJ91183.1};
RX PubMed=21415278; DOI=10.1104/pp.110.171579;
RA Matsumoto T., Tanaka T., Sakai H., Amano N., Kanamori H., Kurita K.,
RA Kikuta A., Kamiya K., Yamamoto M., Ikawa H., Fujii N., Hori K., Itoh T.,
RA Sato K.;
RT "Comprehensive sequence analysis of 24,783 barley full-length cDNAs derived
RT from 12 clone libraries.";
RL Plant Physiol. 156:20-28(2011).
RN [2] {ECO:0000313|Proteomes:UP000011116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Morex {ECO:0000313|Proteomes:UP000011116};
RX PubMed=23075845; DOI=10.1038/nature11543;
RG The International Barley Genome Sequencing Consortium;
RA Mayer K.F., Waugh R., Brown J.W., Schulman A., Langridge P., Platzer M.,
RA Fincher G.B., Muehlbauer G.J., Sato K., Close T.J., Wise R.P., Stein N.;
RT "A physical, genetic and functional sequence assembly of the barley
RT genome.";
RL Nature 491:711-716(2012).
RN [3] {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.7HG0733700.2}
RP IDENTIFICATION.
RC STRAIN=subsp. vulgare
RC {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.7HG0733700.2};
RG EnsemblPlants;
RL Submitted (JAN-2022) to UniProtKB.
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; AK359974; BAJ91183.1; -; mRNA.
DR AlphaFoldDB; F2D7W2; -.
DR STRING; 112509.F2D7W2; -.
DR PaxDb; 4513-MLOC_54524-6; -.
DR EnsemblPlants; HORVU.MOREX.r3.7HG0733700.2; HORVU.MOREX.r3.7HG0733700.2; HORVU.MOREX.r3.7HG0733700.
DR Gramene; HORVU.MOREX.r2.7HG0608910.1; HORVU.MOREX.r2.7HG0608910.1; HORVU.MOREX.r2.7HG0608910.
DR Gramene; HORVU.MOREX.r2.7HG0608910.1.mrna1; HORVU.MOREX.r2.7HG0608910.1.mrna1; HORVU.MOREX.r2.7HG0608910.1.
DR Gramene; HORVU.MOREX.r3.7HG0733700.2; HORVU.MOREX.r3.7HG0733700.2; HORVU.MOREX.r3.7HG0733700.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007358_0_1_1; -.
DR OMA; CESILWE; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000011116; Chromosome 7H.
DR ExpressionAtlas; F2D7W2; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF454; GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000011116};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..935
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015090650"
FT TRANSMEM 588..608
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 644..662
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 830..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 469..810
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 914..935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 759..813
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 935 AA; 102300 MW; 0B202297A4FE7FA3 CRC64;
MGADRLLLLC LALALFAAAA AQRTNPPPRV VSVGALFTYD STIGRAARLA IELAVDDVNA
DRAVLAGTTL NLISQDTNCS GFLGTIEALQ LMEKNVVAVI GPQSSGIGHV ISHVVNELHV
PLLSFAATDP TLSASEYPYF LRSTISDYFE MHAVASIIDY YQWKEVTAIF VDDDYGRGGV
SVLGDALGAK RARISHKAAI PPNSDTDLIN DVLFRANMME SRVFVVHVNP DAGMRIFALA
NKLQMMGAGY VWIVTDWLAA VLDSSGAGDL KDMSYIQGLI VLRQHTPDSD AKKKFIAKWN
NAANNRSIAS GLNSYGFYAY DSVWVVARAI NEYLNSGQQI TFSADPRLHK SNRSTLRLSN
LKIFDGGDQL LQQLLLTNMT GLTGLVQFNA DRNLVRPAYD ILNIGGTGSR LIGYWSNYSG
LSVAAPEILY RKPPNTSTSA QQLHSVVWPG DTTTKPRGWV FPNNGQPLRV GVPNKPSFRE
LVSVGKGPDN VTGYSVDIFN AAIKLLPYPV PCQFITIGDG SKNPNYDDII SRIATNALDA
AVGDFAIVRN RTKIAEFTQP YIEAGLVIVA PVRKANSNAW AFFKPFTLEM WCVTGTLFIF
VGVVVWILEH RTNEEFRGSP RRQVLTIFWF SFSTMFFAHR QNTVSALGRF VLIIWLFVVL
IINSSYTASL TSILTVQQLA TGITGLDNLV ASALPIGYPA GKFVRNYLID ELNIPESRLV
PLSTVEEYAN ALNRGPKDGG VAAVVDEMPC VEIFLSTHCN FRIVGQEFTK EGWGFAFQRD
SPLAADLSTA ILQLSETGQL QRIHDEWLTD PTCGDDDSGL GAVRLGLGSF WGLFLLCALI
CVFALTVYFA RVCWQYSRYS SSEPPGEPSD SAAAVTAATI AQIRPEKPKP TRLGSFKELI
QFADTKEEEI KKVMKRRLSE KDTRGTGSAH SVSSA
//
