ID F2DGJ8_HORVV Unreviewed; 277 AA.
AC F2DGJ8;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 08-NOV-2023, entry version 72.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:BAJ94219.1};
OS Hordeum vulgare subsp. vulgare (Domesticated barley).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX NCBI_TaxID=112509 {ECO:0000313|EMBL:BAJ94219.1};
RN [1] {ECO:0000313|EMBL:BAJ94219.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Shoot and root {ECO:0000313|EMBL:BAJ94219.1};
RX PubMed=21415278; DOI=10.1104/pp.110.171579;
RA Matsumoto T., Tanaka T., Sakai H., Amano N., Kanamori H., Kurita K.,
RA Kikuta A., Kamiya K., Yamamoto M., Ikawa H., Fujii N., Hori K., Itoh T.,
RA Sato K.;
RT "Comprehensive sequence analysis of 24,783 barley full-length cDNAs derived
RT from 12 clone libraries.";
RL Plant Physiol. 156:20-28(2011).
RN [2] {ECO:0000313|Proteomes:UP000011116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Morex {ECO:0000313|Proteomes:UP000011116};
RX PubMed=23075845; DOI=10.1038/nature11543;
RG The International Barley Genome Sequencing Consortium;
RA Mayer K.F., Waugh R., Brown J.W., Schulman A., Langridge P., Platzer M.,
RA Fincher G.B., Muehlbauer G.J., Sato K., Close T.J., Wise R.P., Stein N.;
RT "A physical, genetic and functional sequence assembly of the barley
RT genome.";
RL Nature 491:711-716(2012).
RN [3] {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.1HG0014590.1}
RP IDENTIFICATION.
RC STRAIN=subsp. vulgare
RC {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.1HG0014590.1};
RG EnsemblPlants;
RL Submitted (JAN-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the steroid 5-alpha reductase family.
CC {ECO:0000256|ARBA:ARBA00007742}.
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DR EMBL; AK363015; BAJ94219.1; -; mRNA.
DR AlphaFoldDB; F2DGJ8; -.
DR STRING; 112509.F2DGJ8; -.
DR PaxDb; 4513-MLOC_68045-2; -.
DR EnsemblPlants; HORVU.MOREX.r3.1HG0014590.1; HORVU.MOREX.r3.1HG0014590.1; HORVU.MOREX.r3.1HG0014590.
DR Gramene; HORVU.MOREX.r2.1HG0011190.1; HORVU.MOREX.r2.1HG0011190.1; HORVU.MOREX.r2.1HG0011190.
DR Gramene; HORVU.MOREX.r3.1HG0014590.1; HORVU.MOREX.r3.1HG0014590.1; HORVU.MOREX.r3.1HG0014590.
DR eggNOG; KOG1638; Eukaryota.
DR HOGENOM; CLU_065395_2_0_1; -.
DR OMA; FEVLVFW; -.
DR OrthoDB; 2896758at2759; -.
DR Proteomes; UP000011116; Chromosome 1H.
DR ExpressionAtlas; F2DGJ8; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 1.20.120.1630; -; 1.
DR InterPro; IPR001104; 3-oxo-5_a-steroid_4-DH_C.
DR InterPro; IPR039357; SRD5A/TECR.
DR PANTHER; PTHR10556; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 1.
DR PANTHER; PTHR10556:SF35; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF02544; Steroid_dh; 1.
DR PROSITE; PS50244; S5A_REDUCTASE; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011116};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 170..252
FT /note="Steroid 5-alpha reductase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50244"
SQ SEQUENCE 277 AA; 30010 MW; 59954AFC0AEF1AFC CRC64;
MWPPSLLPAV LYPPPASVFV TAMSVVSFAS LASAGLSELR GQHMAYSKFW HVVSGQQQQQ
KKGGTGGALL SSRDGMLVAY APALVAAAAS FVVPGAVEGL RAELLAAALA VHFLKRVLEV
LFIHRYSGNM PLNTALTISS SYLLSAITMI YAQHLAVGLP DPTTDLLYPG VLLFTVGIAG
NFYHHYLLSQ LRKGGDDDKG YKIPKGGLFE FVTCPHYLFE IIGFFGFAMI SQTVYALAMA
SGTAAYLIGR SFATRRWYES KFEEFPTTIK ALIPYIL
//
