ID   F2I2E7_PELSM            Unreviewed;       299 AA.
AC   F2I2E7;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=4-hydroxythreonine-4-phosphate dehydrogenase {ECO:0000313|EMBL:AEA81412.1};
DE            EC=1.1.1.262 {ECO:0000313|EMBL:AEA81412.1};
GN   OrderedLocusNames=SAR11G3_00937 {ECO:0000313|EMBL:AEA81412.1};
OS   Pelagibacter sp. (strain IMCC9063).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Candidatus Pelagibacterales;
OC   Candidatus Pelagibacteraceae; Pelagibacter.
OX   NCBI_TaxID=1002672 {ECO:0000313|EMBL:AEA81412.1, ECO:0000313|Proteomes:UP000009181};
RN   [1] {ECO:0000313|EMBL:AEA81412.1, ECO:0000313|Proteomes:UP000009181}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMCC9063 {ECO:0000313|EMBL:AEA81412.1,
RC   ECO:0000313|Proteomes:UP000009181};
RX   PubMed=21515764; DOI=10.1128/JB.05033-11;
RA   Oh H.M., Kang I., Lee K., Jang Y., Lim S.I., Cho J.C.;
RT   "Complete genome sequence of strain IMCC9063, belonging to SAR11 subgroup
RT   3, isolated from the Arctic Ocean.";
RL   J. Bacteriol. 193:3379-3380(2011).
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DR   EMBL; CP002511; AEA81412.1; -; Genomic_DNA.
DR   RefSeq; WP_013695577.1; NC_015380.1.
DR   AlphaFoldDB; F2I2E7; -.
DR   STRING; 1002672.SAR11G3_00937; -.
DR   KEGG; pel:SAR11G3_00937; -.
DR   eggNOG; COG1995; Bacteria.
DR   HOGENOM; CLU_040168_0_0_5; -.
DR   OrthoDB; 9801783at2; -.
DR   Proteomes; UP000009181; Chromosome.
DR   GO; GO:0050570; F:4-hydroxythreonine-4-phosphate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR005255; PdxA_fam.
DR   PANTHER; PTHR30004; 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR30004:SF6; D-THREONATE 4-PHOSPHATE DEHYDROGENASE; 1.
DR   Pfam; PF04166; PdxA; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:AEA81412.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009181}.
SQ   SEQUENCE   299 AA;  34372 MW;  5C8F2070CF44C396 CRC64;
     MKKTILILTS DPLSINYEII KKSQNFFKKK LHNKYLFVGD QKDLCNNIKK DNKLIDFLNV
     KRGTNTKVYL KKCFELAFKL LKNKEADGLI NLPLNKRFLP GNYAGFTEYI ADAFNKKGKE
     TMLLYNQNFS VCPNTTHIKI KDVSRNLNQK KIITNITNID NFYKNIPGVK RPMIGVMGLN
     PHSGMDFEKN TEENSVINPA IKKLIKNKIR VIGPLVPDVA FNEVNKKKIN CLVGHYHDQV
     LPTFKYIHKF DAINITLGLP FLRISPDHGT ASNLRNKNLA NPESFIAALK FFEKHYKKI
//