ID F2JT53_CELLD Unreviewed; 634 AA.
AC F2JT53;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN OrderedLocusNames=Clole_3589 {ECO:0000313|EMBL:ADZ85272.1};
OS Cellulosilyticum lentocellum (strain ATCC 49066 / DSM 5427 / NCIMB 11756 /
OS RHM5) (Clostridium lentocellum).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Cellulosilyticaceae;
OC Cellulosilyticum.
OX NCBI_TaxID=642492 {ECO:0000313|EMBL:ADZ85272.1, ECO:0000313|Proteomes:UP000008467};
RN [1] {ECO:0000313|EMBL:ADZ85272.1, ECO:0000313|Proteomes:UP000008467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49066 / DSM 5427 / NCIMB 11756 / RHM5
RC {ECO:0000313|Proteomes:UP000008467};
RX PubMed=21398547; DOI=10.1128/JB.00239-11;
RG US DOE Joint Genome Institute;
RA Miller D.A., Suen G., Bruce D., Copeland A., Cheng J.F., Detter C.,
RA Goodwin L.A., Han C.S., Hauser L.J., Land M.L., Lapidus A., Lucas S.,
RA Meincke L., Pitluck S., Tapia R., Teshima H., Woyke T., Fox B.G.,
RA Angert E.R., Currie C.R.;
RT "Complete genome sequence of the cellulose-degrading bacterium
RT Cellulosilyticum lentocellum.";
RL J. Bacteriol. 193:2357-2358(2011).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
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DR EMBL; CP002582; ADZ85272.1; -; Genomic_DNA.
DR RefSeq; WP_013658548.1; NC_015275.1.
DR AlphaFoldDB; F2JT53; -.
DR STRING; 642492.Clole_3589; -.
DR KEGG; cle:Clole_3589; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_015182_0_2_9; -.
DR Proteomes; UP000008467; Chromosome.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:ADZ85272.1};
KW Cilium {ECO:0000313|EMBL:ADZ85272.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Flagellum {ECO:0000313|EMBL:ADZ85272.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008467};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 13..109
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 339..621
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT COILED 578..605
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 634 AA; 70455 MW; 1E6A222D17B4A12D CRC64;
MGTSPIRFTG LASGMDTESI VKAMMTSYQA KVDKQKQNQT SLEWKRDAWK DMNSKVNSFY
SNYISKLKMS TTFAKNKITT SDNNAIKVNE NSSIPAGTHQ VSVSQIATSA YMKNEKMTAT
TVTPLAETTT LKHLGIDKET TIKLQKVVDG AVVEGEDYAE FKLGPNDTIA TLKDKLAEQD
LELKVTEGKI EITSNKNTAD NEAIKLVASE GNTNFFSKLG VGTTTLKKDQ VVTGKDLNTF
SKSMTLGRLG ITNTNIKINE NSIELTENMT LSELESKIKE ADSNLSVNLD LGEGVQRFFI
SSKKTGDGNN ITIEQEDGGS DILKKLGLYT DPAEESLKGK NAKYTYNGVE YTSSTNDISV
NGLKMTFIAE TTSPVNITAV KDTESLVSFV KEFVTEYNKL IEEINTEIET RPSKTYKPLT
DEQREAMSES EIEKWEKEAK KGLFYRDGQL TQIRDNLRSM IGSGVTGTAY GTLSGVGITT
GQWNEKGKLY FDEAKFTKAL EDDPESVIKL FTGAGDESAA KTAYEKKYGE NSWSSVSETD
RQSYLANTKG IFNRLYDNLN KMVGTSTVNK SYGSFYNDKL IKKQLEDMEK RIDELQDRYD
QKETALYKKF TAMEKAMSTM NTQSSWLSAQ LGSY
//
