ID   F2K2J3_MARM1            Unreviewed;       594 AA.
AC   F2K2J3;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Oxaloacetate decarboxylase alpha subunit {ECO:0000313|EMBL:ADZ90038.1};
DE            EC=4.1.1.112 {ECO:0000313|EMBL:ADZ90038.1};
GN   OrderedLocusNames=Marme_0755 {ECO:0000313|EMBL:ADZ90038.1};
OS   Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 /
OS   MMB-1).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Oceanospirillaceae; Marinomonas.
OX   NCBI_TaxID=717774 {ECO:0000313|EMBL:ADZ90038.1, ECO:0000313|Proteomes:UP000001062};
RN   [1] {ECO:0000313|EMBL:ADZ90038.1, ECO:0000313|Proteomes:UP000001062}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1
RC   {ECO:0000313|Proteomes:UP000001062};
RX   PubMed=22675599; DOI=10.4056/sigs.2545743;
RA   Lucas-Elio P., Goodwin L., Woyke T., Pitluck S., Nolan M., Kyrpides N.C.,
RA   Detter J.C., Copeland A., Teshima H., Bruce D., Detter C., Tapia R.,
RA   Han S., Land M.L., Ivanova N., Mikhailova N., Johnston A.W.,
RA   Sanchez-Amat A.;
RT   "Complete genome sequence of the melanogenic marine bacterium Marinomonas
RT   mediterranea type strain (MMB-1(T)).";
RL   Stand. Genomic Sci. 6:63-73(2012).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP002583; ADZ90038.1; -; Genomic_DNA.
DR   RefSeq; WP_013659943.1; NZ_CP047696.1.
DR   AlphaFoldDB; F2K2J3; -.
DR   STRING; 717774.Marme_0755; -.
DR   KEGG; mme:Marme_0755; -.
DR   PATRIC; fig|717774.3.peg.786; -.
DR   eggNOG; COG0511; Bacteria.
DR   eggNOG; COG5016; Bacteria.
DR   HOGENOM; CLU_000395_4_3_6; -.
DR   OrthoDB; 9760256at2; -.
DR   Proteomes; UP000001062; Chromosome.
DR   GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004736; F:pyruvate carboxylase activity; IEA:UniProt.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   CDD; cd06850; biotinyl_domain; 1.
DR   CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR001882; Biotin_BS.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR003379; Carboxylase_cons_dom.
DR   InterPro; IPR005776; OadA.
DR   InterPro; IPR000891; PYR_CT.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   NCBIfam; TIGR01108; oadA; 1.
DR   PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR   PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   Pfam; PF02436; PYC_OADA; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR   SUPFAM; SSF51230; Single hybrid motif; 1.
DR   PROSITE; PS00188; BIOTIN; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   4: Predicted;
KW   Biotin {ECO:0000256|ARBA:ARBA00023267};
KW   Lyase {ECO:0000313|EMBL:ADZ90038.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001062}.
FT   DOMAIN          8..268
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
FT   DOMAIN          516..594
FT                   /note="Lipoyl-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50968"
SQ   SEQUENCE   594 AA;  63984 MW;  74A7185DDAACE05A CRC64;
     MTTTKQPLGI TDVVLRDAHQ SLFATRLRID DMLPIAEKLD KVGFWSLESW GGATFDSCIR
     FIGEDPWDRI RELKKAMPNT PQQMLLRGQN LLGYRHYADD VVAKFVERAA TNGVDVFRIF
     DAMNDPRNLE QAIKSVKEVG KHAQGTLSYT KSHVHTTKTW VDYAKTLEDM GADSIAIKDM
     SGILTPYDAF ELVGLLKEQT DLEVQLHAHA TSGLSDMTIL KAVEAGIDRV DTAISSMSMT
     YGHSATESVV AALQGTNRDT GLDLALLEEI AAYFRVVRKK YAKFEGSLRG TDSRILIAQV
     PGGMLTNMEN QLKEQGAADK FDEVLEEIPK VRQDLGMIPL VTPTSQIVGT QAVLNVLTGE
     RYKSISKETA GVLKGEYGAA PAEFNKELQT RVLDGAEPIT CRPADLLEPE VEKLTQELET
     LASEKGIALS NESIDDVLTY ALFPQIGLKF LENRGDASAF EPVPTGEELV AKAPVEAGPA
     VYTVSVSGQS YVVEVTDGGD ISQIQPVGSA SAAPVAAAAP APASGGEDVP APLAGNIFKV
     LVSPGQQVQE GETIMILEAM KMETEISAPK SGVVGSIYVK EGDAVQVGQA LVSL
//