ID F2K387_MARM1 Unreviewed; 2331 AA.
AC F2K387;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=RHS repeat-associated core domain {ECO:0000313|EMBL:ADZ90140.1};
GN OrderedLocusNames=Marme_0865 {ECO:0000313|EMBL:ADZ90140.1};
OS Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 /
OS MMB-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=717774 {ECO:0000313|EMBL:ADZ90140.1, ECO:0000313|Proteomes:UP000001062};
RN [1] {ECO:0000313|EMBL:ADZ90140.1, ECO:0000313|Proteomes:UP000001062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1
RC {ECO:0000313|Proteomes:UP000001062};
RX PubMed=22675599; DOI=10.4056/sigs.2545743;
RA Lucas-Elio P., Goodwin L., Woyke T., Pitluck S., Nolan M., Kyrpides N.C.,
RA Detter J.C., Copeland A., Teshima H., Bruce D., Detter C., Tapia R.,
RA Han S., Land M.L., Ivanova N., Mikhailova N., Johnston A.W.,
RA Sanchez-Amat A.;
RT "Complete genome sequence of the melanogenic marine bacterium Marinomonas
RT mediterranea type strain (MMB-1(T)).";
RL Stand. Genomic Sci. 6:63-73(2012).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; CP002583; ADZ90140.1; -; Genomic_DNA.
DR STRING; 717774.Marme_0865; -.
DR KEGG; mme:Marme_0865; -.
DR PATRIC; fig|717774.3.peg.906; -.
DR eggNOG; COG3209; Bacteria.
DR HOGENOM; CLU_000852_0_0_6; -.
DR Proteomes; UP000001062; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR Gene3D; 3.30.2310.30; -; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 2.
DR Gene3D; 2.180.10.10; RHS repeat-associated core; 3.
DR InterPro; IPR038233; Colicin_D/E5_nuclease.
DR InterPro; IPR021964; Colicin_E5_C.
DR InterPro; IPR038234; Colicin_E5_C_sf.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR022385; Rhs_assc_core.
DR InterPro; IPR031325; RHS_repeat.
DR InterPro; IPR003284; Sal_SpvB.
DR InterPro; IPR006530; YD.
DR NCBIfam; TIGR03696; Rhs_assc_core; 1.
DR NCBIfam; TIGR01643; YD_repeat_2x; 1.
DR PANTHER; PTHR46580:SF3; ATP_GTP-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR46580; SENSOR KINASE-RELATED; 1.
DR Pfam; PF12106; Colicin_E5; 1.
DR Pfam; PF13517; FG-GAP_3; 2.
DR Pfam; PF05593; RHS_repeat; 1.
DR Pfam; PF03534; SpvB; 1.
DR SUPFAM; SSF102824; Colicin D/E5 nuclease domain; 1.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001062};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..2331
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003284423"
FT DOMAIN 2245..2330
FT /note="Colicin E5 ribonuclease"
FT /evidence="ECO:0000259|Pfam:PF12106"
FT REGION 2165..2296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2170..2260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2266..2283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2331 AA; 259649 MW; AA335E45FFDEA410 CRC64;
MLRSIASSLF VFLLSLSSIS TYASESWETG AYRLLEADYN GDGLADLIFD PTTTVRVTTT
QTITVNHRTG REPMVMVNDS QGGYSLLRNA DQSIIDRLSY KYADYKLIYG ELTEDGLNDI
VLQPKSDNGK LWLVQSEFKN QYTIDGYNSF ELNSHSISYL STSVEITDGK LVIGSNLQGL
SPVPIQKIEK RVVLGDNQIW VEAIRTTSSS NNNYRILWID YNNDGKSDIL FDPTTFAISQ
AGTVSTIVPI STGYERVVLL NDGDGGFTLV RNANEVPLKA STTSIADYKL IEGDLSGDAK
NDFVLQPGSD YGRLIVVQSE WSTAAAATVY TAGQLDFNRF GADTIDLHIA NGQLFSYSEQ
FSQSTVTTTI TDNTVHLGRY KTYSSTAQRI PGTIDGKAEV DVSGAARYRI PLEVAAGING
LKPSLSLSYN SNRGRGILGK GWAISGISSI TRCQSNLADD DKIRAVNLDD QDRFCLDGQK
LKVVSGTYGS VNSEYRTLIN NFEKVVFKGE HWVVYEKNGN QRVYGATAHA RVSAEETIVK
WAISQKRDAA NNTIDFDYLP DTKESTFVPI TIRYANKSIQ FKYEQVAATS VGYMAGSGVR
WTNKNRLQSI KMLGADNASN AQKVFRTYHF RYEKGSFDNE DLLASIELCG RDKECFVPTQ
FNYESGEKEA LAAYHNGQGA SFANIKSKTL TSKGYRYFPN VDLNGDGYKD ILLISRYVNS
QTATTYSWYG KKAGGFTYKG TQGVTGSYSG RTSTYEVFDA NGDGKDDIVV IRQVGKAKTY
SWLSNGSGKF SLVSSHNEIG STSGRYYRTF DANGDGLKDI IEFYAKGSGR AATIWKSNRN
GTFSYFKNTT YVGRKNSRDD RPMDVNGDGI LDIVYLDKAD DNVEAVTYKN TNGKFSHSGT
TRIGKKDSKY LQADLNGDGL TDFLVISKSG SSAKAKSWLN DGKGKFIAVF DISSVGGWSD
RQYFTTDINR DGSQDLVEIY KCDKNRCLTT WINNGVGYFN WHKGGKSLSN YARYYGVDSN
GNGSLDVVGI KELSSKVREG TGEDREWVNH YYPQFKTWQT QSDINLNKLA SITDGLRNET
HFDYTSMVHN TVYKKSGNKT TFPVLPAIAP RYLVSEMKQS DGIGGENTFS YRYEGLISHL
QGIGSLGFKK RQISDHTNKR ATVIEYSQDW QNRTYGAPLL ERTCIEGSET LFSYTGFDYC
GEGKGQKIKE VTTTWGTNKS SSGVYAYHPA SKVTSLWDQN GNEISAQKTD EESYDFTHGL
ATKETLTTGK GFNGTNITDS VQTEQRDWSY HITSSWLIKP ATLKTTVDIT GNTDARTVNT
TNWSYNSTGL LERVINEPNT SEEFITEYRN FDRGLPKTIE ERWKANGTAN AGLDFTSRTE
KRTYDVNGYL ATQTNALGHK ESFEYDGSLG KLNKYENANG QETHYKYNGV GFLSQLIEPA
TTTDFIYQFC ASGCYDNMSY SATKTTQGQP TSQTFYDAFG RERLTRTKLL SGKWRYTKQS
YNAHGLTESK SVPYLEGNEP ALHEYEYDLL GKVTLHNKPK STASTEYQYE GARVTRTEHF
NGKSLTTIEE HNALGQKTAV NDALGSTIRY QYNGLGLLTK TTNVDGSEIK IDYNRSGHRT
KLDDPDKGVI NYTVNALGLV AKESLSGATN QFTFDKLGRM ITRTTSEGVA SWQYDQGNNA
KGLVSSVNQG SYSETYDYDA LSRLHSKSVT YGDGQTARQS WQYGLYNRLD TVTYPGNYGI
TYQYNDYGYL KQIHRAGDTS DVHWQALSMD AWGNVDQYLL DGSLKTVKQF DKASGLVNNI
QTSWFGFAST KVQDAQYQYD DIGNLTTRTQ STWSDSSHGY QQTQNETYTY DKLHRLSAWT
DQAGSHTMQY AANGNILNKP GIGSYRYGQQ ESGCSALPGP HAVSWTQSKG NLCYDGRGNM
ISGGGKTLTY TSFDKPKVMI QGGSRIEVAY GPDLSRYKRT DKKDGKVATT TWYMGHEFER
ELSANGKLTE RLYLGDFGFV ERIKKAGQSD VYEQTRYLLK DHIGSIIGIA EGNGYVLLSQ
FTYDPWGKRS QVYHDFENKD LLDFTQIGRL GFTGHEMLDP VGLIHMNGRV YDPELARFVT
PDPVVSDPYD TQAFNRYSYV HNRPTSFTDP TGYFIPALIG IVRVAVIAAP YAVKLYKVSK
KALSTLRKQA QKPKKPDSKT GGKNNEASKP EDGPKQPSKS ESASKNETPE KNQKSLEDKS
KGNGDNGVEG KDGGEGRGGV GKKVTTQFEK KIENQMGKRG WDKDSVNSTI DNPNKTVSTR
DTRWNSDGTR RDDPATAYIR EDDHYVVRNN NDGTIVQISN RNKADWKSPF E
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