ID   F2LR32_BURGS            Unreviewed;      1100 AA.
AC   F2LR32;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=Multidrug resistance protein MdtC {ECO:0000313|EMBL:AEA65199.1};
GN   OrderedLocusNames=bgla_2g27830 {ECO:0000313|EMBL:AEA65199.1};
OS   Burkholderia gladioli (strain BSR3).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=999541 {ECO:0000313|EMBL:AEA65199.1, ECO:0000313|Proteomes:UP000008316};
RN   [1] {ECO:0000313|EMBL:AEA65199.1, ECO:0000313|Proteomes:UP000008316}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BSR3 {ECO:0000313|EMBL:AEA65199.1,
RC   ECO:0000313|Proteomes:UP000008316};
RX   PubMed=21478339; DOI=10.1128/JB.00420-11;
RA   Seo Y.S., Lim J., Choi B.S., Kim H., Goo E., Lee B., Lim J.S., Choi I.Y.,
RA   Moon J.S., Kim J., Hwang I.;
RT   "Complete genome sequence of Burkholderia gladioli BSR3.";
RL   J. Bacteriol. 193:3149-3149(2011).
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DR   EMBL; CP002600; AEA65199.1; -; Genomic_DNA.
DR   RefSeq; WP_013691523.1; NC_015376.1.
DR   AlphaFoldDB; F2LR32; -.
DR   STRING; 999541.bgla_2g27830; -.
DR   KEGG; bgd:bgla_2g27830; -.
DR   eggNOG; COG0841; Bacteria.
DR   HOGENOM; CLU_002755_1_2_4; -.
DR   Proteomes; UP000008316; Chromosome 2.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 3.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF34; MULTIDRUG RESISTANCE PROTEIN MDTC; 1.
DR   Pfam; PF00873; ACR_tran; 2.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        336..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        360..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        387..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        431..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        463..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        530..549
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        923..941
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        948..968
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        974..999
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1020..1039
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1051..1077
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1100 AA;  117256 MW;  82D2803505BF9CF8 CRC64;
     MNFSRFFIRR PVATTLLALG IALSGLFAFV KLPVSPLPRV DFPTISVFAN LPGASPATVS
     TSVTSPLERH LGSIAGVTQM TSTSSLGNAL ISLQFVLERD LNGAARDVQA AINAARADLP
     ASLKSNPTFQ KVNLADTPIM VLSVTSDIAP PSRVYDAAST VLQQALSQIE GIGEVDVFGA
     ASPAVRVELE PHALFHYGIG LEDVRAALAS ANANSPKGMI EVGPNRYQLY TNDQASQASQ
     YRDLVVAYRN NAAVRLTDVG SVIDSVEDLR NLGLANGKRA VLVILYRSPG ANIIDAVDRV
     KAALPRLSAA LPPDVDLGSV LDRSVTIRSS LADTEHTLVV AVALVVMVVF VFLRNWRATL
     IPTAAVPVSI IGTFGAMYVL GFSIDNLSLM ALIVATGFVV DDAVVVLENI MRHIENGKPR
     MQAALDGARE VGFTVVSISL SLIAVFLPIL LMTGLIGRLF REFAMTLSLA IAVSLVVSLT
     LTPMMCARLL PEAGSHRKEG RLSRWLERGF ERLQSGYDRT LQWALRHRRI TLLSLIATVG
     LNMALFVVVP KGFFPQQDTG VLIGGIQVDQ STSFQAMQLK FVEMMKIIQS DPNVLSIAGF
     RGGRTTNAGF MFVTLKDKRD RKLSADQIIE HLRPQLERVA GAQTFLQAAQ DLGGGGGRQT
     NAQYQFSLYG DSPEELYKWG DKLAAALKKK PQLTDVNSDQ QQGGLEAMVH IDRATAARLG
     ITPLQIDNTL YDAFGQRQVS TIYNPLNQYH VVMELAPKYW QDPEMLKQVW ISTTGGSASG
     VAQTNAAAGT FVAGGGGAGG AKSSASTAQA VSTDAARNAA LNSIAATGKA GTSSGEAVST
     SKSTMIPLSA IASFGPGTTP IAINHEGPFV AVTISFNLPP GKALSDARTV IYQTMREIGV
     PASINAGFSG TAEEFEKALR DQLLLIIAAL AAIYIVLGIL YESYIHPITI LSTLPSAGVG
     ALLALLISGT EFDIIGLIGI FLLIGIVKKN AILMIDYAVV AAREGKSSFE AIHEACRLRF
     RPILMTTMAA LFGTLPLVFG HGDGAELRAP LGITLAGGLI VSQVLTLYTT PVVYLYMDRL
     RLRSERRRAR RAGLPPAAGA
//