ID F2LUW8_HIPMA Unreviewed; 690 AA.
AC F2LUW8;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN OrderedLocusNames=Hipma_0603 {ECO:0000313|EMBL:AEA33573.1};
OS Hippea maritima (strain ATCC 700847 / DSM 10411 / MH2).
OC Bacteria; Campylobacterota; Desulfurellia; Desulfurellales; Hippeaceae;
OC Hippea.
OX NCBI_TaxID=760142 {ECO:0000313|EMBL:AEA33573.1, ECO:0000313|Proteomes:UP000008139};
RN [1] {ECO:0000313|EMBL:AEA33573.1, ECO:0000313|Proteomes:UP000008139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700847 / DSM 10411 / MH2
RC {ECO:0000313|Proteomes:UP000008139};
RX PubMed=21886857;
RA Huntemann M., Lu M., Nolan M., Lapidus A., Lucas S., Hammon N.,
RA Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S.,
RA Liolios K., Pagani I., Ivanova N., Ovchinikova G., Pati A., Chen A.,
RA Palaniappan K., Land M., Hauser L., Jeffries C.D., Detter J.C.,
RA Brambilla E.M., Rohde M., Spring S., Goker M., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA Mavromatis K.;
RT "Complete genome sequence of the thermophilic sulfur-reducer Hippea
RT maritima type strain (MH(2)).";
RL Stand. Genomic Sci. 4:303-311(2011).
RN [2] {ECO:0000313|Proteomes:UP000008139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700847 / DSM 10411 / MH2
RC {ECO:0000313|Proteomes:UP000008139};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Peters L., Kyrpides N., Mavromatis K., Pagani I., Ivanova N.,
RA Mikhailova N., Lu M., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S.,
RA Schroeder M., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Hippea maritima DSM 10411.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
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DR EMBL; CP002606; AEA33573.1; -; Genomic_DNA.
DR RefSeq; WP_013681614.1; NC_015318.1.
DR AlphaFoldDB; F2LUW8; -.
DR STRING; 760142.Hipma_0603; -.
DR KEGG; hmr:Hipma_0603; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_7; -.
DR InParanoid; F2LUW8; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000008139; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:AEA33573.1};
KW Cilium {ECO:0000313|EMBL:AEA33573.1}; Coiled coil {ECO:0000256|SAM:Coils};
KW Flagellum {ECO:0000313|EMBL:AEA33573.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000008139};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 110..133
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 203..224
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 244..261
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 282..298
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT COILED 319..346
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 690 AA; 75575 MW; 3B421B250E28EA9F CRC64;
MDKELNLKSI KLSDFSVVLT VVIVFAVLVI PLPGFLIDFL VSTSFALALL IFFISVYVQK
PLDFSTFPSI LLAVTLFRLS LNVATTRAIL LHGSQSPEAA GKMIETFGYF VVGGNYVVGL
IVFIILVIIN FVVITKGAGR VAEVAARFTL DAMPGKQMSI DADLNAGLID EKEARRRRDE
IARQADFYGA MDGASKFVRG DAIAGLLITA INIIGGIIIG VLQHHMSLSA AASRYTVLTI
GDGLVSQLPA LTVSTAAGII ITRSSEEANL STNIVNQLIN QYQTLYIAAI VLAIMAFVPG
MPTFHLLILA AVLSGIAYSI SSTKKKREAE EEVEQAKAEE PEEEITVESI EEAIKVDLLE
LKIGYGLISF VEEQNGGGLI KRIKLMRKQI ATELGVIIPS IRIRDDLNLD RNEYVFLIKG
VEVARYSVYP DKFLAMKPGG SKDIEGIPTK EPAFGLDAIW IDAKDKSSAI VKGYTVVDPI
TVIITHLTEL VKSHISEIFT RQDASKLLDS IKGDYPKIIE ELTSQLSLGV IHKILKNLLN
EGIPVRDMIT IAETLSDYAA YTKDPEILTE YVRAALAKHI TNKYKDENNT INVITLGSNV
DGIINANIKE QGGMTYLDLP PNISEKLLEK TQEAISNAVE NGIEPIILTS PKIRRYFKGF
IERFFPRVPV ISYAEIAEGI QIKSISSIEL
//
