ID F2NTL6_TRES6 Unreviewed; 440 AA.
AC F2NTL6;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Pseudouridine synthase {ECO:0000313|EMBL:AEB15005.1};
GN OrderedLocusNames=Tresu_2136 {ECO:0000313|EMBL:AEB15005.1};
OS Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=869209 {ECO:0000313|EMBL:AEB15005.1, ECO:0000313|Proteomes:UP000006852};
RN [1] {ECO:0000313|EMBL:AEB15005.1, ECO:0000313|Proteomes:UP000006852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33096 / DSM 2489 / 6091
RC {ECO:0000313|Proteomes:UP000006852};
RX PubMed=21886863;
RA Han C., Gronow S., Teshima H., Lapidus A., Nolan M., Lucas S., Hammon N.,
RA Deshpande S., Cheng J.F., Zeytun A., Tapia R., Goodwin L., Pitluck S.,
RA Liolios K., Pagani I., Ivanova N., Mavromatis K., Mikhailova N.,
RA Huntemann M., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA Brambilla E.M., Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Detter J.C.;
RT "Complete genome sequence of Treponema succinifaciens type strain (6091).";
RL Stand. Genomic Sci. 4:361-370(2011).
RN [2] {ECO:0000313|Proteomes:UP000006852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33096 / DSM 2489 / 6091
RC {ECO:0000313|Proteomes:UP000006852};
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Peters L., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G.,
RA Teshima H., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S.,
RA Wellnitz S., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of chromosome of Treponema succinifaciens DSM 2489.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002631; AEB15005.1; -; Genomic_DNA.
DR RefSeq; WP_013702258.1; NC_015385.1.
DR AlphaFoldDB; F2NTL6; -.
DR STRING; 869209.Tresu_2136; -.
DR KEGG; tsu:Tresu_2136; -.
DR eggNOG; COG0564; Bacteria.
DR HOGENOM; CLU_037416_0_0_12; -.
DR OrthoDB; 305739at2; -.
DR Proteomes; UP000006852; Chromosome.
DR GO; GO:0140098; F:catalytic activity, acting on RNA; IEA:UniProt.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR CDD; cd02869; PseudoU_synth_RluA_like; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR006224; PsdUridine_synth_RluA-like_CS.
DR InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR PANTHER; PTHR21600; MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE; 1.
DR PANTHER; PTHR21600:SF100; RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00849; PseudoU_synth_2; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR PROSITE; PS01129; PSI_RLU; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006852}.
FT DOMAIN 228..387
FT /note="Pseudouridine synthase RsuA/RluA-like"
FT /evidence="ECO:0000259|Pfam:PF00849"
SQ SEQUENCE 440 AA; 50143 MW; 9955DD397A33FD60 CRC64;
MFPPFDEALA FKYCKEIISL LEEKKLSLVY TTEKISAERF ANGIMIGVLV AKNSAQENKI
FFTVSGISRK IEGKFQDAIF VEPIVSSKKI MSALQKNDKE IHLLTEKLKA CRKEEVQDLQ
FRRSAFTSES LEKVHELYSF YCFDGKNRPL KQICKNRLPP TGTGDCCAPK LLNFAFKNNL
TPLSMCEVFY GKSTENKISD CKYSPCDERC GLILPEILGL KILYRDNDLI VVNKQSGLLS
VPGRGPEKQD CIVNRLKKLF PECIEQPSVH RLDMETSGLM ILAFTKDAHR NLCRQFEEGL
VQKKYVALLD GILAKKGIPQ SGTMELYFRL DIENRPHQIW DSVYGKKAIT EWKILDVEKY
LSPLENKKNV TRVLFIPHTG RTHQLRLASA DSHGFGVPII GDTLYGHCEP GERLMLHSCY
IKFTHPSTGK VMEFNCECDF
//
