ID   F2PR13_TRIEC            Unreviewed;      1336 AA.
AC   F2PR13;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Tip120 {ECO:0000313|EMBL:EGE04331.1};
GN   ORFNames=TEQG_03359 {ECO:0000313|EMBL:EGE04331.1};
OS   Trichophyton equinum (strain ATCC MYA-4606 / CBS 127.97) (Horse ringworm
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=559882 {ECO:0000313|Proteomes:UP000009169};
RN   [1] {ECO:0000313|Proteomes:UP000009169}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4606 / CBS 127.97 {ECO:0000313|Proteomes:UP000009169};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
CC   -!- SIMILARITY: Belongs to the CAND family.
CC       {ECO:0000256|ARBA:ARBA00007657}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS995732; EGE04331.1; -; Genomic_DNA.
DR   VEuPathDB; FungiDB:TEQG_03359; -.
DR   eggNOG; KOG1824; Eukaryota.
DR   HOGENOM; CLU_007157_0_0_1; -.
DR   Proteomes; UP000009169; Unassembled WGS sequence.
DR   GO; GO:0010265; P:SCF complex assembly; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039852; CAND1/CAND2.
DR   InterPro; IPR013932; TATA-bd_TIP120.
DR   PANTHER; PTHR12696:SF0; CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1; 1.
DR   PANTHER; PTHR12696; TIP120; 1.
DR   Pfam; PF08623; TIP120; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1158..1324
FT                   /note="TATA-binding protein interacting (TIP20)"
FT                   /evidence="ECO:0000259|Pfam:PF08623"
FT   REGION          362..393
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          487..537
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        490..504
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1336 AA;  145423 MW;  E8FF5A201D99A900 CRC64;
     MSFHKQAIQQ ALGPLMVKLT DPDPDIRYMS LNDLLSLIEG CSLPYFLQDH SSCNRMVQGL
     LKSLEDQNGE VQNVALKCIG PLATRSPPDV LSSFIDKLAL LTSSQTIDTS VPNTALRMIL
     AALPKPNINL INSREVQLSY EAVSMVLIPR LIGTPTRGNL PTAAPGMIVN DPAKGFSSDA
     IDVLIDVVRS YGPMLNDEEL FELLQTVLRV IENDHAGTVV TKRALTAISM LSIHLSDTQL
     SGFVSGLIES FKSPHLTINR RRHLIAAVSA MARSTPAKFG PYLKLLAPFV LSAVSEKEMN
     EMDDDMSDDG EHDPKQDELR ETALVSLDTL LGYCGSEMQP YLNDCIAAAL RYLKYDPNVA
     ELEDDEEMGG TQDESSDDGA TEEPDDDNDA FDDFEEEEGY SDIDDLSWKV RRCAAKVLYT
     IVSTQGRNAR AVEDGSIYQK IAPALLSRFT KEREESVKVE VVATMTGLVR KTSDLATGPN
     LFYSDPFSQA RSSRKRRRQD SNATVIDLES DFPPPSASDT PIAKPSTPQP GPQTDLADLT
     PGIVQALTKL WKGAPIPLKQ GVILLLKALA LVRYGGLADY LQRIEDPIAD ALKTSGLSGG
     VTVSAGSNSV SAGNLQVEAL GLIAAISETH PSGSLSPFLI ALIPGVVACV NNRDFKVSSE
     ALGAIEQIVV ALTPPRVSVD DRDLGLQLEK LYDIVVEKVT DNSTDLGVRQ RGIHVLGVML
     SRTSGPEGRR FITLEQRRKA LLVLLERLKN ETTRVAAARA IDDIALLARQ SDDVEASWLG
     YVTLELAAQL RKVDRTLRDV CLGALKSIAM NSQTRQYLDK HTTEGLRVAI SPLISADDLH
     LLTPALVIFA KLLPHYGPDL VNDSIITQLC AAVQGTLTGT ALKAYILLVR VIGEQGAGAK
     LMKALLQTVG VNGDSAVVGK AIGTLLVYSG PKVGVTTEDF LVELKTAQDN QRKCLALAIL
     GEIGLRMGAK SPLDPQLFIT NFNSPSDKVR LAAAVALGNA GASNVDAYLP VILEGLEKSK
     SSKYLLLHSL KEILQHPEDV KTHVAPFATR LWQILLSASD DEDNRTVGAE CIGRLSLIDP
     ATYIPQLQEY LSHPNATIRG TVISAFRYTL ADSSSTYNET LRPLIVPVLV TILNDSDLAN
     HRLALTTLNS AIHNKTALVL PHLPQLLPAV MGDTNLKPEL VREVQMGPFK HKVDDGLELR
     KSAYETLYTC LDVAFSAVNL PEVFDRIIAG IEDEQDIRTL CTLMISKLMT LAPEETLARL
     DAFSNSFRVV LSVKPKESAV KQELEKAQEA SIGVLKVSRE LQMAFPAAEA SNDHHSWKSY
     VEWISRDFSQ LLRSID
//