ID F2PRV1_TRIEC Unreviewed; 862 AA.
AC F2PRV1;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Potassium transport protein {ECO:0000256|PIRNR:PIRNR002450};
GN ORFNames=TEQG_03487 {ECO:0000313|EMBL:EGE04619.1};
OS Trichophyton equinum (strain ATCC MYA-4606 / CBS 127.97) (Horse ringworm
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=559882 {ECO:0000313|Proteomes:UP000009169};
RN [1] {ECO:0000313|Proteomes:UP000009169}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4606 / CBS 127.97 {ECO:0000313|Proteomes:UP000009169};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TrkH potassium transport family.
CC {ECO:0000256|ARBA:ARBA00009137, ECO:0000256|PIRNR:PIRNR002450}.
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DR EMBL; DS995734; EGE04619.1; -; Genomic_DNA.
DR AlphaFoldDB; F2PRV1; -.
DR VEuPathDB; FungiDB:TEQG_03487; -.
DR eggNOG; KOG1341; Eukaryota.
DR HOGENOM; CLU_005947_0_1_1; -.
DR Proteomes; UP000009169; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030007; P:intracellular potassium ion homeostasis; IEA:UniProtKB-UniRule.
DR InterPro; IPR003445; Cat_transpt.
DR InterPro; IPR004773; K/Na_transp_Trk/HKT.
DR InterPro; IPR015958; Trk_fungi.
DR NCBIfam; TIGR00934; 2a38euk; 1.
DR PANTHER; PTHR31064:SF30; HIGH-AFFINITY POTASSIUM TRANSPORT PROTEIN-RELATED; 1.
DR PANTHER; PTHR31064; POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED; 1.
DR Pfam; PF02386; TrkH; 1.
DR PIRSF; PIRSF002450; K+_transpter_TRK; 2.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002450};
KW Potassium {ECO:0000256|ARBA:ARBA00022958, ECO:0000256|PIRNR:PIRNR002450};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR002450};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002450}.
FT TRANSMEM 34..58
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 95..120
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 423..447
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 487..505
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 556..576
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 621..638
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 680..698
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT TRANSMEM 704..728
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR002450"
FT REGION 137..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 256..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..805
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 817..862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..358
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..853
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 862 AA; 96640 MW; 2CB410529289C3EA CRC64;
MDTVKAAIER WKLSPEIREK LWAIKRKTPV LKDLHYNFIC LHYAWIIGVT LVGSIILYPG
GNMSYVDALF FASGSATQSG LNTIDVNKLY TYQQVWLWMG SMIANPIVIN SAVVFVRLYW
FEQRFQHVVR EVKALRRSRS RSRATTREPD DTNDLHRAEA GVRGRDIVVL RNTDGHAQGR
FLDAPKKEPE TTSESDSSIP PGEGQGETAT NENGQSTSNT SLKTSDALLA PSHFPGDARI
QWSVPPSDNE RHITFLEHQR RQTGALRIPS PREYDRGGMP EALDETDGAD LARNATVQSD
PPAELTGTSL PTSLGPMNQH ITIDEPNITR TRKATHSRGG ERDRDRDRDR DRDGEETSTI
RRVTSRRSMV PSFMRSRTLE QLQQDAPYLS WEPTIGRNSA FVDLSEMQRE ELGGIEYRAL
KTLAIVLIGY FFFFHLLGIV CMVPWILNTR WGEVVRAAGQ GRPWWAVFSS GSAFNDQGFT
ITPDSMLSFY DAIFPMLLMT FLILIGNTGF PCMLRFVIWF FSMIVPKGSG VWEELKFLLD
HPRRCFTLLF PSSANWWLFW VLVILNGVDL IFFVVLDLND PDVTRIPGGI RFVDGLFQAA
ATRTAGLSVI GLTTLHPAIQ VSYMIMMYIS VFPIAISVRR TNVYEERSLG IYSDPDEYNE
NEKEPSFVGA HLQRQLSFDI WYIFLGLFVI SIIEGSRLDN PKDLGFSLFA VLFEVVSAYG
TVGLSLGYPD SNTSFSAQFH TLSKLVIIAM EIRGRHRGLP YALDRAVLLP SEALHRKEAD
DASKRLRRRS SNVSALSSAT GRASGLYRDD GGLMARLSQQ QQQQQQQLSS GGGVLGSSSD
APPPTASSAR GARRLSTHQE DA
//
