ID F2PZY2_TRIEC Unreviewed; 368 AA.
AC F2PZY2;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Checkpoint protein {ECO:0000256|PIRNR:PIRNR011312};
GN ORFNames=TEQG_06577 {ECO:0000313|EMBL:EGE07450.1};
OS Trichophyton equinum (strain ATCC MYA-4606 / CBS 127.97) (Horse ringworm
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=559882 {ECO:0000313|Proteomes:UP000009169};
RN [1] {ECO:0000313|Proteomes:UP000009169}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4606 / CBS 127.97 {ECO:0000313|Proteomes:UP000009169};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SIMILARITY: Belongs to the HUS1 family. {ECO:0000256|ARBA:ARBA00005563,
CC ECO:0000256|PIRNR:PIRNR011312}.
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DR EMBL; DS995760; EGE07450.1; -; Genomic_DNA.
DR AlphaFoldDB; F2PZY2; -.
DR VEuPathDB; FungiDB:TEQG_06577; -.
DR eggNOG; KOG3999; Eukaryota.
DR HOGENOM; CLU_035754_0_0_1; -.
DR Proteomes; UP000009169; Unassembled WGS sequence.
DR GO; GO:0030896; C:checkpoint clamp complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:InterPro.
DR GO; GO:0000077; P:DNA damage checkpoint signaling; IEA:InterPro.
DR Gene3D; 3.70.10.10; -; 1.
DR InterPro; IPR016580; Cell_cycle_HUS1.
DR InterPro; IPR007150; Hus1/Mec3.
DR PANTHER; PTHR12900:SF0; CHECKPOINT PROTEIN; 1.
DR PANTHER; PTHR12900; MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1; 1.
DR Pfam; PF04005; Hus1; 1.
DR PIRSF; PIRSF011312; Cell_cycle_HUS1; 3.
PE 3: Inferred from homology;
FT REGION 114..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 39034 MW; 12199EAEFC1812DA CRC64;
MRFKSQLTNV ATFSKFTASL SSLGKVCWVR LEDEVVRFSI IPDQGTQVWA QLPIHTVFDS
YSFSSVAKVI NLEVPIGALH RALKSATGAT SAQLRLTKKG NQPQLALTVV TSSWTSGKGA
SNSDEPARAS GSRPANSQSL ENGGALSGIP AAELLQDGPR ERETIVTQEI PIRVLHPSAV
EGVHEPRCRD PDVHIILPSL IQLKSISERF TKLATDAASS KAGNASAGGN GNGPALAGGS
HSSGPKLELS ANMHGSLKLA IATDALRISS VWAGLVNPPL DQADMTQSEI AQLPSERMRA
RAADGEEGWA KVRIDGKDWG RVLSVGRLSP KVVACFIHET ALVLYVYLPG GIGGEDSCLT
YYINSYAS
//
