ID F2Q496_TRIEC Unreviewed; 289 AA.
AC F2Q496;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Fumarylacetoacetate hydrolase domain-containing protein 2A {ECO:0000313|EMBL:EGE08964.1};
GN ORFNames=TEQG_07958 {ECO:0000313|EMBL:EGE08964.1};
OS Trichophyton equinum (strain ATCC MYA-4606 / CBS 127.97) (Horse ringworm
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=559882 {ECO:0000313|Proteomes:UP000009169};
RN [1] {ECO:0000313|Proteomes:UP000009169}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4606 / CBS 127.97 {ECO:0000313|Proteomes:UP000009169};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
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DR EMBL; DS995791; EGE08964.1; -; Genomic_DNA.
DR AlphaFoldDB; F2Q496; -.
DR VEuPathDB; FungiDB:TEQG_07958; -.
DR eggNOG; KOG1535; Eukaryota.
DR HOGENOM; CLU_028458_2_1_1; -.
DR Proteomes; UP000009169; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR PANTHER; PTHR11820:SF112; FUMARYLACETOACETATE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G02370)-RELATED; 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR SUPFAM; SSF56529; FAH; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EGE08964.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 72..281
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
SQ SEQUENCE 289 AA; 31292 MW; 6ADAFD45DD76CE11 CRC64;
MPAFSRLVRF LAKDGLVYHG DAILPSGVSD LAKTTRARVI KGEVFGNHQV TDQVQEVKKL
LCPLARKEIK TIRCLGLNYA GHAKESNMPL PKYPILFFKP ITAASGPTDD IPVPQMAQEC
EGLDYECELV IIIGKEAHNV PKSKALEYVL GYSVGNDVSH REWQIKRGGS QWGIGKGFDG
WAPFGPGIVT SKIIPDPNAL QILTKVNGKA VQNSNTKDMI FGVAETVAFL SQGTTLLPGD
IIFTGTPQGV GMGRKPQVWL KDGDRVEVSL ENVGTCSNKV VHVNGSSKL
//
