ID F2R419_STRVP Unreviewed; 523 AA.
AC F2R419;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CCA58391.1};
GN OrderedLocusNames=SVEN_5105 {ECO:0000313|EMBL:CCA58391.1};
OS Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS 4526 / NBRC 13096 / PD 04745).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA58391.1, ECO:0000313|Proteomes:UP000006854};
RN [1] {ECO:0000313|EMBL:CCA58391.1, ECO:0000313|Proteomes:UP000006854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10712 {ECO:0000313|EMBL:CCA58391.1};
RX PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA Pullan S.T., Bibb M.J., Merrick M.;
RT "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT provides new insights into global nitrogen regulation in actinomycetes.";
RL BMC Genomics 12:175-175(2011).
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DR EMBL; FR845719; CCA58391.1; -; Genomic_DNA.
DR RefSeq; WP_015036289.1; NZ_CP029197.1.
DR AlphaFoldDB; F2R419; -.
DR STRING; 953739.SVEN_5105; -.
DR GeneID; 69867172; -.
DR KEGG; sve:SVEN_5105; -.
DR PATRIC; fig|953739.5.peg.242; -.
DR eggNOG; COG4585; Bacteria.
DR HOGENOM; CLU_000445_20_11_11; -.
DR OrthoDB; 227596at2; -.
DR Proteomes; UP000006854; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006854};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 104..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 181..246
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT DOMAIN 288..390
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
FT REGION 325..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 523 AA; 55041 MW; DC9C98FDEAF783E9 CRC64;
MRDAPREPLR ERLFDLLLWM LLGVPVLLKS DPNDGGSWPR VAAGLLVLAG CVAVSRRWPL
VSLAVTVAAS LPATLELFTP SYSLALVAFG YLAGRRQEHT RAALWLFGAI AVAGLVLTSV
TGTSLGQWFT LLLVLALAVV APWLIGRYVR QYDRLVRSGW ELADRMEREQ AAVADRERLR
ERSRIAGDMH DSLGHDLALI AIRAGALEVS PELGPEQQRA AGELRRAAAE ATGRLRDIIG
VLREDDAAAP TSPPGETVEE LVARARSSGL AVTLATTPVP TLPGMSGLAL HRVVQEGLTN
AAKHAPGAAV TVTVAPEAAD VRVEVVSGPG TDGPRGGSAA GPGGAGPAGS GSGGRGLVGL
DERVRLAGGT LTHRTTGDGG FALTAVLPRK APAPLPAAPT SARELDRARR EVRKGLARAI
WVPLALLAAL GTLMAGVALW TQAQSYLEPA AYAKIRIGQT LAELDETTDD WPEHPLDSAP
QAAPPEPAGM DECRYYRSTM LAAIPVYRLC FVGGHLADKA EVP
//
