ID F2R787_STRVP Unreviewed; 949 AA.
AC F2R787;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN OrderedLocusNames=SVEN_0492 {ECO:0000313|EMBL:CCA53779.1};
OS Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS 4526 / NBRC 13096 / PD 04745).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA53779.1, ECO:0000313|Proteomes:UP000006854};
RN [1] {ECO:0000313|EMBL:CCA53779.1, ECO:0000313|Proteomes:UP000006854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10712 {ECO:0000313|EMBL:CCA53779.1};
RX PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA Pullan S.T., Bibb M.J., Merrick M.;
RT "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT provides new insights into global nitrogen regulation in actinomycetes.";
RL BMC Genomics 12:175-175(2011).
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DR EMBL; FR845719; CCA53779.1; -; Genomic_DNA.
DR RefSeq; WP_015031698.1; NZ_CP029197.1.
DR AlphaFoldDB; F2R787; -.
DR STRING; 953739.SVEN_0492; -.
DR GeneID; 69862701; -.
DR KEGG; sve:SVEN_0492; -.
DR PATRIC; fig|953739.5.peg.6337; -.
DR eggNOG; COG2909; Bacteria.
DR HOGENOM; CLU_006850_1_2_11; -.
DR OrthoDB; 3178131at2; -.
DR Proteomes; UP000006854; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006854}.
FT DOMAIN 854..919
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
FT REGION 822..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 912..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 949 AA; 100200 MW; 854026D09BBD4EBE CRC64;
MVLVERERHL TQLSALLERC LDGAGSVVVL RGPVAVGRTE LLHTFAERVA GPRVRFLGAA
ASPEERQLPF GLLSQLLHGA GAAYAERAEA LIGRPGRPEG EAGPQVLEGV ARILLDMSAE
DPLLLGVDDV SHADTDSLRC LLFLARRLRR ARVMLVLSDQ DGSGSRHADV RGELSRLPYC
TQIRLDPLSC DGVAALLAHD LDAHVAHSLA AGAFAVTGGN PLLVRALAED WEAHARAAGA
EPPTALVVGD RFAERAVSCL HRFGPDALAV ARAVAVIGEA PDADLVARLT GLGAIETRAL
LELLGTSGLL REGRYRHPVA QAAVLRDFGA AGRVAWHRSA AALLHADGGP PVSVALQLIA
AGDTDEPWAP AVLQESAARA TAGGQVDFAV DCLELAHTLA DDEQQRAVSR AVLAEAEWRL
DPARVVRHLG QLTDALHRGH LTDRQSLSVL EHLLWHGRVD EAATALDRLA RTESGPDAAE
LGAVRACLEL CYPAQRHHRT TRSPAPVRTP PPGSAPSLVA TVLAAVRGEG AVSGDHLWQG
LRTDEPLTRI ALGLLALARP ERLATVAPWC LPVLADAAGH EGPDWRGLVT AARADAALLR
GELPAAGTFA AEALAESSAA SWGVLAGAPL ACLLVTAVET GRLEEAAAQL NVPLPAALME
TPFGLRYLRA RGQYHLAIDR PYAALSDFRA CGRLLRDWAA DGPRQLPWRI DAAQAMVRLG
RRAEARALLE EQLDGLPVDD ERTLGRALRQ LAATLEPHER PPLLGDAVEA LQAAGDRVEL
AHALADLGNA HAAAGDSRRA RPVLRRAWRA ARECHAERLA RVLRPGAAST PPAGAASGGP
GRSGGPRASG GVLGGEQAAE LSAAERRVGG LAARGHSNRQ IAQRLCITVS TVEQHLTQVY
RKLGVRSRTD LPGFLEDEEE PSGVNSTAGS PRTDPLLADA FSHSSPYSP
//
