ID F2R7E4_STRVP Unreviewed; 448 AA.
AC F2R7E4;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Putative two-component system sensor kinase {ECO:0000313|EMBL:CCA56229.1};
GN OrderedLocusNames=SVEN_2943 {ECO:0000313|EMBL:CCA56229.1};
OS Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS 4526 / NBRC 13096 / PD 04745).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA56229.1, ECO:0000313|Proteomes:UP000006854};
RN [1] {ECO:0000313|EMBL:CCA56229.1, ECO:0000313|Proteomes:UP000006854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 /
RC PD 04745 {ECO:0000313|Proteomes:UP000006854};
RX PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA Pullan S.T., Bibb M.J., Merrick M.;
RT "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT provides new insights into global nitrogen regulation in actinomycetes.";
RL BMC Genomics 12:175-175(2011).
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DR EMBL; FR845719; CCA56229.1; -; Genomic_DNA.
DR RefSeq; WP_015034145.1; NZ_JABVZO010000240.1.
DR AlphaFoldDB; F2R7E4; -.
DR STRING; 953739.SVEN_2943; -.
DR GeneID; 69865071; -.
DR KEGG; sve:SVEN_2943; -.
DR PATRIC; fig|953739.5.peg.5137; -.
DR eggNOG; COG4585; Bacteria.
DR HOGENOM; CLU_000445_20_1_11; -.
DR OrthoDB; 227596at2; -.
DR Proteomes; UP000006854; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CCA56229.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006854};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 52..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 213..278
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT COILED 174..201
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 448 AA; 47218 MW; AE8942F988BB1225 CRC64;
MTTTGAERDA DRVGNWWWWG RRRGAVLDGG LALVSAVECA LEGVGSAEQA SLPVPLGVLF
GLAVGSVLLV RRRWPIVVVL VSIAVTPAEM GFLMGIVGLY SLAASEVPRR ITALLAGMST
LAVFVVTVVR MRQDIAHADV GEPDIDPSGW YVPVVAVFMT LGLNAPPLLF GLYIGARRRL
MESLRERADS LEQELSLLAD RAEQRAQWAR QEERTRIARE MHDVVAHRVS LMVVHAAALQ
AVALKDPQKA VKNAALVGDM GRQALTELRE MLGVLREDAV PAAPAPVPLA AVGRAAAAAA
EAAADDGPCL DALEDLCEQS RLAGAVVELV VLGDARAHPP EVERTAYRVV QEALTNVHKH
AAGAEVVVRL AHRDGEVAMQ VENGPCPSDA GAADVRLPSG GNGLVGMRER VLRLGGVFVA
GATDAGGFRV SAVLPTVTPL SGGVAALR
//
