ID F2R823_STRVP Unreviewed; 228 AA.
AC F2R823;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=DNA-binding response regulator KdpE {ECO:0000313|EMBL:CCA58832.1};
GN OrderedLocusNames=SVEN_5546 {ECO:0000313|EMBL:CCA58832.1};
OS Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS 4526 / NBRC 13096 / PD 04745).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA58832.1, ECO:0000313|Proteomes:UP000006854};
RN [1] {ECO:0000313|EMBL:CCA58832.1, ECO:0000313|Proteomes:UP000006854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10712 {ECO:0000313|EMBL:CCA58832.1};
RX PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA Pullan S.T., Bibb M.J., Merrick M.;
RT "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT provides new insights into global nitrogen regulation in actinomycetes.";
RL BMC Genomics 12:175-175(2011).
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DR EMBL; FR845719; CCA58832.1; -; Genomic_DNA.
DR RefSeq; WP_015036727.1; NZ_JABVZO010000268.1.
DR AlphaFoldDB; F2R823; -.
DR STRING; 953739.SVEN_5546; -.
DR GeneID; 69867612; -.
DR KEGG; sve:SVEN_5546; -.
DR PATRIC; fig|953739.5.peg.695; -.
DR eggNOG; COG0745; Bacteria.
DR HOGENOM; CLU_000445_30_8_11; -.
DR OrthoDB; 9802426at2; -.
DR Proteomes; UP000006854; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd17620; REC_OmpR_KdpE-like; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.250.690; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR039420; WalR-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR48111:SF50; KDP OPERON TRANSCRIPTIONAL REGULATORY PROTEIN KDPE; 1.
DR PANTHER; PTHR48111; REGULATOR OF RPOS; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000006854}.
FT DOMAIN 3..116
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 129..228
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 129..228
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT MOD_RES 52
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 228 AA; 25457 MW; FA796CF0F2BC3CA5 CRC64;
MTRVLVVDDE PQIVRALVIN LKARKYEVDA APDGATALRL AAERHPDVVV LDLGLPDMDG
VEVIKGLRGW TRVPILVLSA RQTSDEKVEA LDAGADDYVT KPFGMDELLA RLRAAVRRAE
PVGGAEDGVV VVETEGFTVD LAAKKVHRDG RDVRLTPTEW HLLEVLVRNG GRLVSQKQLL
QEVWGPSYGT ETNYLRVYMA QLRRKLESDP SHPRHFVTEP GMGYRFER
//
