ID F2R8C8_STRVP Unreviewed; 205 AA.
AC F2R8C8;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Regulatory protein, TetR {ECO:0000313|EMBL:CCA53846.1};
GN OrderedLocusNames=SVEN_0559 {ECO:0000313|EMBL:CCA53846.1};
OS Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS 4526 / NBRC 13096 / PD 04745).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA53846.1, ECO:0000313|Proteomes:UP000006854};
RN [1] {ECO:0000313|EMBL:CCA53846.1, ECO:0000313|Proteomes:UP000006854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 /
RC PD 04745 {ECO:0000313|Proteomes:UP000006854};
RX PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA Pullan S.T., Bibb M.J., Merrick M.;
RT "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT provides new insights into global nitrogen regulation in actinomycetes.";
RL BMC Genomics 12:175-175(2011).
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DR EMBL; FR845719; CCA53846.1; -; Genomic_DNA.
DR RefSeq; WP_015031765.1; NZ_JABVZO010000466.1.
DR AlphaFoldDB; F2R8C8; -.
DR STRING; 953739.SVEN_0559; -.
DR GeneID; 69862764; -.
DR KEGG; sve:SVEN_0559; -.
DR PATRIC; fig|953739.5.peg.740; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_069356_12_0_11; -.
DR OrthoDB; 63332at2; -.
DR Proteomes; UP000006854; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR041490; KstR2_TetR_C.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF256; TRANSCRIPTIONAL REGULATOR, TETR FAMILY-RELATED; 1.
DR Pfam; PF17932; TetR_C_24; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000006854};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..74
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 37..56
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 205 AA; 21386 MW; 8227F743F0D94C27 CRC64;
MAYRKSPAEL ARLSSAREHL VQQATDVVAE VGWAQTSVNA VAAAAGIAAG SVYQHFPSKA
ALAVEVFRRA SGREVEVLGE VLSSPGDPVD RLVRGVEVFA RRSLERRGLA YALLAAPAEP
AVGAERLEFR RRYRALFAEV VSEGVAGGAL PRQNPEVTAA ALTGAVAEVL VDPLGAPGAD
SAEQLIGELT AMALRCLGAT QDGED
//
