ID F2RBQ5_STRVP Unreviewed; 328 AA.
AC F2RBQ5;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=RNA polymerase sigma-70 factor {ECO:0000313|EMBL:CCA56766.1};
GN OrderedLocusNames=SVEN_3480 {ECO:0000313|EMBL:CCA56766.1};
OS Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS 4526 / NBRC 13096 / PD 04745).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA56766.1, ECO:0000313|Proteomes:UP000006854};
RN [1] {ECO:0000313|EMBL:CCA56766.1, ECO:0000313|Proteomes:UP000006854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 /
RC PD 04745 {ECO:0000313|Proteomes:UP000006854};
RX PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA Pullan S.T., Bibb M.J., Merrick M.;
RT "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT provides new insights into global nitrogen regulation in actinomycetes.";
RL BMC Genomics 12:175-175(2011).
CC -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC {ECO:0000256|ARBA:ARBA00010641}.
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DR EMBL; FR845719; CCA56766.1; -; Genomic_DNA.
DR AlphaFoldDB; F2RBQ5; -.
DR STRING; 953739.SVEN_3480; -.
DR KEGG; sve:SVEN_3480; -.
DR PATRIC; fig|953739.5.peg.5704; -.
DR eggNOG; COG1595; Bacteria.
DR HOGENOM; CLU_047691_22_0_11; -.
DR Proteomes; UP000006854; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 3.10.450.50; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR014303; RNA_pol_sigma-70_ECF.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR NCBIfam; TIGR02957; SigX4; 1.
DR PANTHER; PTHR30173:SF36; ECF-FAMILY RNA POLYMERASE SIGMA FACTOR-RELATED; 1.
DR PANTHER; PTHR30173; SIGMA 19 FACTOR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF08281; Sigma70_r4_2; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006854};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 26..88
FT /note="RNA polymerase sigma-70 region 2"
FT /evidence="ECO:0000259|Pfam:PF04542"
FT DOMAIN 125..176
FT /note="RNA polymerase sigma factor 70 region 4 type 2"
FT /evidence="ECO:0000259|Pfam:PF08281"
SQ SEQUENCE 328 AA; 35547 MW; BC349F7581BBB0CC CRC64;
MTVTQGRYPP RITGMALIAS DVDRFETARP RLEAIAYRLL GSVSEAEDAV QETFLRWHAA
DTGRIDVPEA WLTKVLTNLC LNQLTSARAR RETYVGRWLP EPLLAGDPML GPADTAEQRD
SVSYAVLVLL ERLAPAERAV YVLREAFAYP HREIAAILDI TEAACQQTYH RAKKHIADGR
ARTEIDEAAA RRIVEEFLAA ATSGRTEPLV QLLTQDAVSV GDGGGKIPAR TKAFEGALAV
ATFLRGLFKP AKSKRALVGG VPEIYATTAN GGPAVVAVVD GRIVGITCLE VTADGIAAVR
SQVNPDKLVR ATERWAAEEH PEGPLYTL
//
