ID F2SD28_TRIRC Unreviewed; 662 AA.
AC F2SD28;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 2.
DT 13-SEP-2023, entry version 44.
DE RecName: Full=CorA family metal ion transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=TERG_00728 {ECO:0000313|EMBL:EGD84450.2};
OS Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=559305 {ECO:0000313|EMBL:EGD84450.2, ECO:0000313|Proteomes:UP000008864};
RN [1] {ECO:0000313|Proteomes:UP000008864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4607 / CBS 118892 {ECO:0000313|Proteomes:UP000008864};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GG700648; EGD84450.2; -; Genomic_DNA.
DR AlphaFoldDB; F2SD28; -.
DR STRING; 559305.F2SD28; -.
DR VEuPathDB; FungiDB:TERG_00728; -.
DR eggNOG; ENOG502QPTQ; Eukaryota.
DR HOGENOM; CLU_007127_10_0_1; -.
DR InParanoid; F2SD28; -.
DR OMA; TNANHNT; -.
DR OrthoDB; 1358357at2759; -.
DR Proteomes; UP000008864; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12829; Alr1p-like; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR044089; Alr1-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR PANTHER; PTHR21535:SF51; MANGANESE RESISTANCE PROTEIN MNR2; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000008864};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT REGION 43..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..85
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..403
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 662 AA; 74745 MW; 7842DEDDE5EAB3BE CRC64;
MLFSVTVVFL AGNANTPRNQ PMMRPRRESR LAQSFRPDQL LVESPTSSRT KIRRHETLPE
DDFAITDDRS PLLTSSAQNG GALRGYGSDS RSPYTMPPGM GSPTSRRSPQ NSYTPDAFSA
SRQGYDVNNP PSMPGSPKII PNNMGYDETV ITGPEFVRQQ SPEALSCHSL PMDAVVSVDA
DSRRPGLQSR HGSMSRSPAD LQRRRTLTLP VEEDVCFPAS GLSDLGEEDL QSHIPTGGDT
RERRRRSRRV WPDLSVLDEW SQHEKEARSG GTRSKRIDEP VLIGGRLRTR NLAWKQDEEE
EAPYRFTYFN EDFQSTLHSQ TLSELEQPGQ TFRDLFIPEP PLLEDDSSDE EDDSPAYSGI
TGRDKHPSIS TNANHNTNNL PDLISDNPDS TSQQPTNGNS RAPSPKKEPR YGPRPTFWLD
VLSPTDSEMR IIAKAFGIHA LTAEDIMMQE AREKVELFRN YYFINYRTFE QDVNSPDFLE
PVNMYVVVFR EGLLSFHFSR TPHPANVRRR IRQLKDYLIL SADWISYAII DDITDVFGPL
IHAIEEEVDE IDDKILRLHS DDKEMGSDQN NEKSAALEES GSGTNMLRQV GACRKKVMGL
YRLLGNKADV IKGFAKRCNE FWEVAPKSEI GLYLGDIQDH ILTMTSNLTH YETYIGPIPF
VA
//
