ID F2SWR4_TRIRC Unreviewed; 325 AA.
AC F2SWR4;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN ORFNames=TERG_07013 {ECO:0000313|EMBL:EGD90786.1};
OS Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=559305 {ECO:0000313|EMBL:EGD90786.1, ECO:0000313|Proteomes:UP000008864};
RN [1] {ECO:0000313|Proteomes:UP000008864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4607 / CBS 118892 {ECO:0000313|Proteomes:UP000008864};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
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DR EMBL; GG700656; EGD90786.1; -; Genomic_DNA.
DR RefSeq; XP_003232161.1; XM_003232113.1.
DR AlphaFoldDB; F2SWR4; -.
DR STRING; 559305.F2SWR4; -.
DR GeneID; 10372185; -.
DR VEuPathDB; FungiDB:TERG_07013; -.
DR eggNOG; KOG2774; Eukaryota.
DR HOGENOM; CLU_007383_19_0_1; -.
DR InParanoid; F2SWR4; -.
DR OMA; DTELWIC; -.
DR OrthoDB; 1472464at2759; -.
DR Proteomes; UP000008864; Unassembled WGS sequence.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd05238; Gne_like_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43103:SF3; ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE; 1.
DR PANTHER; PTHR43103; NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Reference proteome {ECO:0000313|Proteomes:UP000008864}.
FT DOMAIN 4..211
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 325 AA; 35449 MW; 7595DB7BC2E62C23 CRC64;
MPSILITGAN GFVGQELATG LLNACPDTRL TLTDVTVAPP VPPSAKLEDA SRITSIKADL
TSQAAVDELI SSPSQYDAVY ILHGIMSGAS EANFDLGMKI NFFSVHYMFE RLRKVIPGVK
VIFASSLAVY GPTPPGFKIN ERNIPPLPTS SYATAKVATE LLLNDYSRRG FLDGRSVRLP
TVTVRAGAPT GAASSFASGI IREPLKGEKS VIPVKKDTEL WICSPYVVVE NMIYAKDIPK
ENFGDSRAVN LPGIKVSVTE MLDVLEQVGG KEKRALVEEK YDEAVDKIVQ GWSPNFDITW
AKELGFKEDI SFLESVKRYA RDHVH
//
