ID F2TVK7_SALR5 Unreviewed; 847 AA.
AC F2TVK7;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Xenotropic and polytropic murine leukemia virus receptor xpr1 {ECO:0000313|EMBL:EGD72103.1};
GN ORFNames=PTSG_00119 {ECO:0000313|EMBL:EGD72103.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
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DR EMBL; GL832955; EGD72103.1; -; Genomic_DNA.
DR RefSeq; XP_004998675.1; XM_004998618.1.
DR AlphaFoldDB; F2TVK7; -.
DR EnsemblProtists; EGD72103; EGD72103; PTSG_00119.
DR GeneID; 16067526; -.
DR KEGG; sre:PTSG_00119; -.
DR eggNOG; KOG1162; Eukaryota.
DR InParanoid; F2TVK7; -.
DR OMA; LYQTMFL; -.
DR OrthoDB; 7162at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14475; SPX_SYG1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF103; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 2.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:EGD72103.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 274..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..528
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 540..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..218
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 469..673
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT REGION 797..847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..847
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 847 AA; 97219 MW; D4D508B12BBDC153 CRC64;
MKFGLTLFNN AVPEWRPAYV DYERLKKKLQ EISNAFPRTV RNLHPRVTTD VSPDFKTEEE
VEEEERLEAI SNSNEEKAFM LAVDAELDKV NKFFLEQDDK ARKTCDDLEA QLAALYVAHQ
TGGEHAVAAV RSKNARRRAR AVLRERRARL SAKLTWWCHK PSRILNSQTK QLEKAFQEYY
RNLDMLRAYR NLNNTAFYKI MKKHDKVTGL TMSPTVLAKV SAAPFMTSDL EKEIRRIEQV
FTERLEHGDR RRAMQKLRVP VDAFQPFDWT TFGLGLWAMF FFFCMGIILV VALRSRVADY
PDHRVMFAMY RGLLYPLIML AFVAINMYTW RKFHVNYVLI FGLDHRRHTN YIKMLGTAGL
LMAVWSVSVF AYLFQDELGT TVRPWSAVAL LCVLVAYWAK PWGSMRRARY WLARVVGRMV
AAPFFDVRFE DFWLADQFNS LVVILLDLQF TICYVSKSRF GPMAHDGHHC RSSENVLRAV
IAALPAWWRL MQCLRRFRDT RKYHHIHNAL KYSSSVVVVI FSTLAGVAKD NGQLVGESPT
GTALFVMWIL ACLVNTSYSA FWDLKHDWGL FAKNAKHMWL RRDMLYPVPI YYLAMVNDVV
FRLSWTLSIS VGYFDLFFSD GLVALLSFFE MWRRFVWNFF RVENEHVNNC GEFRAVRHIP
LPFEYVPAET EWELLRGHDG SQRRPPFAHD SSVNDAFGGG RPMSLSVGSA AQHARSHASL
SGYLASPQHT RDDDGDVMRA YDTTARQDVT VYRSDTPGSL YAPPGGLDGA AFRLRSMTFS
HPLDSTLDGL YAANDAAGGD VDDDDDDDDP SRPLLGASSI NRNESSTVHG DYRSFSPTYS
PLSSSDD
//
