ID F2TXU4_SALR5 Unreviewed; 693 AA.
AC F2TXU4;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Fork-head domain-containing protein {ECO:0000259|PROSITE:PS50039};
GN ORFNames=PTSG_00908 {ECO:0000313|EMBL:EGD76203.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; GL832956; EGD76203.1; -; Genomic_DNA.
DR RefSeq; XP_004998378.1; XM_004998321.1.
DR AlphaFoldDB; F2TXU4; -.
DR STRING; 946362.F2TXU4; -.
DR EnsemblProtists; EGD76203; EGD76203; PTSG_00908.
DR GeneID; 16078972; -.
DR KEGG; sre:PTSG_00908; -.
DR eggNOG; KOG2294; Eukaryota.
DR InParanoid; F2TXU4; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20024; FH_FOXJ2-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45881; CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR45881:SF1; FORK HEAD PROTEIN HOMOLOG 2; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 93..170
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 93..170
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 233..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 331..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 439..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..301
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..388
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 75411 MW; 9FD3654BEDC1A1A9 CRC64;
MNRHYPHMHP ATMDVVAGGP AATMRPAASA SNSLDDSLTD IGWVSETHAG THDCLSTPMK
RKPRTAQLSD LATSEHVIDI IRAADLSEYD DKKPPFSYAT LIVAVIAVSR KGQLTLNEIY
KGLCSMFPYF ATTQSGWKNS IRHNLSLHKY FKRVPKKEGE PGKGSYWTVN CEEFVEAQNA
IRPTAPNIKV CDDDMLVPQP EFELSYANDS GLHSSTYGMD GSYVSSNATF HQQGHIHPAH
PSATPPAAMY FSTPAASGTS IPRTHDASSS SAVHRQRPAS ATPTCTQNAG TSQLQQCHQQ
QHEAIQRSLS CASAPPSMHD SPYSLGHFQL PQQQHQQQQQ AKHNSGSARD DENKGSSTRR
SSGSKGHSKS RKSKKKSKHS RHKKHGTRVL ADRTNTMSRH GNDSGMDTRE DGLACKAPKV
NTAPTHARNW QQQQPRMHAF GGAHQHPSAA LPSPLAQPGT TSSPSCAVGL VFSSPQGKSA
RKHAQQQRKD KSRGGRGTTS GTNSSSHLAH AQQAVVKTEP MSDVSEPIQQ QGGEGEAQES
VVAGADMSSA VPMTPPRLMG VDVGFFTSPV AATHGAFMLS SPQARGYFQH SYAHASGQTT
YPQQPQQHQQ QQQQQQQQYQ QYQYHQYMSQ QYSQQPMQST SAYPPQSQQL LGTPGRGGLF
MVPHSPIRFL GSPARGGVPD FVASSPMRGY QLF
//
