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Database: UniProt
Entry: F2U026_SALR5
LinkDB: F2U026_SALR5
Original site: F2U026_SALR5 
ID   F2U026_SALR5            Unreviewed;       838 AA.
AC   F2U026;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   16-OCT-2019, entry version 35.
DE   SubName: Full=G-protein-coupled inward rectifier potassium channel {ECO:0000313|EMBL:EGD80754.1};
GN   ORFNames=PTSG_01342 {ECO:0000313|EMBL:EGD80754.1};
OS   Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX   NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN   [1] {ECO:0000313|Proteomes:UP000007799}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA   Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA   Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q.,
RA   Gargeya S., Alvarado L., Berlin A., Chapman S.B., Chen Z.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heilman E., Heiman D., Howarth C., Mehta T., Neiman D., Pearson M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT   "Annotation of Salpingoeca rosetta.";
RL   Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822}.
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DR   EMBL; GL832958; EGD80754.1; -; Genomic_DNA.
DR   RefSeq; XP_004997315.1; XM_004997258.1.
DR   STRING; 946362.XP_004997315.1; -.
DR   EnsemblProtists; EGD80754; EGD80754; PTSG_01342.
DR   GeneID; 16077912; -.
DR   KEGG; sre:PTSG_01342; -.
DR   InParanoid; F2U026; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000007799; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007799};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000313|EMBL:EGD80754.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822}.
FT   TRANSMEM    263    285       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    328    349       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      226    356       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      364    521       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION       50    161       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      178    201       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      533    566       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      584    788       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     74    131       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    141    156       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    180    201       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    584    600       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    608    624       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    655    712       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    742    756       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    762    788       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   838 AA;  91594 MW;  D64820490665EDF6 CRC64;
     MQTTNHGIAY HNERKASFLS AASSLSLASR SGQGSAAARP RPPRIAATAA SEDDPYDMDH
     SHHHHHQHHN NTINDDNHSN AATNNTHTHL APSSHISFSS SFDPRRTRQT YTETPSPRRS
     SAPSSAWDKA SPRQGSALVR KPTYVRSSNP SPTRKLFKPH DSTLARLSTL RLASDALGKH
     SATASPQQSQ SPGATWNHTQ KHGRLSRNLI RSMRMTQISH GRGGLITKHG QTRMFEHVSG
     LQAWLANFKD MYNFLVNLPS ATLVGLFSLF YTCSFLLFGL FWYLLFRSDA RCLAEVDDFA
     TAFLFSVETQ TTIGYGSKHV RGECEAGIFL LLVQVVMGKL MDAVLLGLIT ARLTRPDNRV
     YTLRCSKHAV VAKRDGKQYL MIRIGDMRQR RAPLVNCEVK LLLVMDHITE EGEHIPFYTQ
     RLVVDSGSNS NTPFLAVPNE LLHLIDESSP LFGMTPGALR RRHAEIVLIL GGQIASLGLN
     VELRSSYLPP EIKFGHRFQQ ICCRLADGSC FTDWSHFDSL VIDEDEVYGI ATHKYDDDDD
     EDDGGGEGDS DDERGNGMMF VPQAGDDKAV LGKKRHRWAR FGRQQWRKHD ADDEVEKWNT
     SGSDEGVVAS RRRGEGEGGD DSRNDSGTHT SSNENSKPRH DRKKSLKGRG RVSTHRRSSS
     LVAPAMSATT AVNPRSPSSS SRAADATSIL AEAAVTSQTP PNAASQPTTA PTPGRGGALV
     TSGMGQHATV LPGAVPRASD DWPSSSEDEH GGHGVHRGSV SRSCMRASQQ AALSQSTGGT
     QADLSQHTSG IALRAYDVGL VERTMETKLG PEDRDRIASI SRHASMASSH KNVSISSS
//
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