ID F2U717_SALR5 Unreviewed; 721 AA.
AC F2U717;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=TrkA-C {ECO:0000313|EMBL:EGD83649.1};
GN ORFNames=PTSG_04255 {ECO:0000313|EMBL:EGD83649.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL832963; EGD83649.1; -; Genomic_DNA.
DR RefSeq; XP_004995153.1; XM_004995096.1.
DR AlphaFoldDB; F2U717; -.
DR STRING; 946362.F2U717; -.
DR EnsemblProtists; EGD83649; EGD83649; PTSG_04255.
DR GeneID; 16075733; -.
DR KEGG; sre:PTSG_04255; -.
DR eggNOG; ENOG502QPZM; Eukaryota.
DR InParanoid; F2U717; -.
DR OMA; CLFVMCA; -.
DR OrthoDB; 276814at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR43652; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR PANTHER; PTHR43652:SF2; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 35..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 493..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 622..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 244..336
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 343..429
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT REGION 660..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..680
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 721 AA; 77704 MW; 5ED6BE6B1F71EEFF CRC64;
MASTTASIST APLTTTSSSM NMTNNIMADD NDAPLWQGIV TLCLLGVMLV AMAKELAPPD
MLMMGILVLF VPMGIITINE AVEGFSNTGM LTVAVLFPVA AGVQLTGAVE PLRRLLERRT
RPARGELASV PKVLSWIMLP IAALSAFLNN TPVVAMMIPL IEKLGQRIGV APSKLLIPLS
YASILGGTCT LIGTSTNLVV VGLVSERVEG FSMGIFEIGQ VGLPVLFAGI AYVLLLAARV
LPDRQSVTTA IVRPKEYITC MFVKKASEAS NTTLEGKTVL EAGLRSLPGL FLIQIERENG
VIVTAPSPDC ILQGGDKLFF AGKVDSVLSL SQVRGLRLAE DDEHEVDLNR LRGDDILVEA
VVAPHSALVH RSVKAARFRT RFKAAIIAVH RHGVRINQKI GDIVLQAGDT LLLVTNKDFV
KLYQSQDHFA LVSEVDGHRN LRWNKAPIAV ILTVAMIALS VAEVIDLLTA ALFAAAGLVL
FRCMSASEIR SAINLEVLLV IAAAFGLSNA LVNSGAAELM ARAVVLASKP TGVTGLYIMV
YLTTVLLSAV VTNNAAITIM FPVAFQAAMD LEEDFFPLLL LLMMGASSSF MTPTGYQTNL
MVYGPGGYTF MDFLKFGGGL QIWLGVITVA VVVTLEFWYL WAVGMLGLAI AVFIFSPKPK
PKPRRETDVD VERGPNSDTE SPPRKEVYYY QPDLGLAKLE CFDDEEERSM TVQHALYADF
A
//
