ID F2UBV5_SALR5 Unreviewed; 365 AA.
AC F2UBV5;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Kynurenine 3-monooxygenase {ECO:0000313|EMBL:EGD73971.1};
GN ORFNames=PTSG_05665 {ECO:0000313|EMBL:EGD73971.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; GL832967; EGD73971.1; -; Genomic_DNA.
DR RefSeq; XP_004993534.1; XM_004993477.1.
DR AlphaFoldDB; F2UBV5; -.
DR STRING; 946362.F2UBV5; -.
DR EnsemblProtists; EGD73971; EGD73971; PTSG_05665.
DR GeneID; 16074111; -.
DR KEGG; sre:PTSG_05665; -.
DR eggNOG; KOG2614; Eukaryota.
DR InParanoid; F2UBV5; -.
DR OMA; REFMFIA; -.
DR OrthoDB; 2250465at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR46028; KYNURENINE 3-MONOOXYGENASE; 1.
DR PANTHER; PTHR46028:SF2; KYNURENINE 3-MONOOXYGENASE; 1.
DR Pfam; PF01494; FAD_binding_3; 2.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033, ECO:0000313|EMBL:EGD73971.1};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000313|EMBL:EGD73971.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 339..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..155
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
FT DOMAIN 210..250
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 365 AA; 40759 MW; 8540B301ABB78814 CRC64;
MKVVIVGGGL VGALEACFMA KRGHEVLLFE TRKDLRKEPR YSGYSINLAL SIRGIDALKH
AGVDHKIVSK GIPMRARMIH SHSGKLSKQP YGTKDQAILS VDRRGLNEEL LTAAEKYKGV
KIYFQHKLRR MNTSNNTCVF EDKDHKEVRV QADLITLFMP FDKFESIKTD ADIISFFEAE
FPDSLPLLGR DNLIHDFNTN PTSPLITVKC SKIAAARCCL LGDAAHAIVP FYGQGMNAGF
EDCLVLEDCL NAESDIEKAM KLFSDTRTKD VHAIADLALY NYIEMRDLVN SSWFLFRKKV
DNVLHWLMPN TFIPLYTMVT FTRIPYATVI AANEKQKKVV NVGLGLAALG GIAGAALLAK
RYLAK
//
