ID F2UJT9_SALR5 Unreviewed; 1760 AA.
AC F2UJT9;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN ORFNames=PTSG_08483 {ECO:0000313|EMBL:EGD77388.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; GL832977; EGD77388.1; -; Genomic_DNA.
DR RefSeq; XP_004990732.1; XM_004990675.1.
DR STRING; 946362.F2UJT9; -.
DR EnsemblProtists; EGD77388; EGD77388; PTSG_08483.
DR GeneID; 16071290; -.
DR KEGG; sre:PTSG_08483; -.
DR eggNOG; KOG0165; Eukaryota.
DR InParanoid; F2UJT9; -.
DR OMA; FVCYLQS; -.
DR OrthoDB; 53079at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR CDD; cd21223; CH_ASPM_rpt1; 1.
DR CDD; cd21224; CH_ASPM_rpt2; 1.
DR Gene3D; 1.20.5.190; -; 6.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR22706:SF1; ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ISOFORM X1; 1.
DR PANTHER; PTHR22706; UNCHARACTERIZED; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00612; IQ; 15.
DR SMART; SM00015; IQ; 21.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50096; IQ; 13.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799}.
FT DOMAIN 705..855
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 239..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..339
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1760 AA; 200614 MW; 490CA160794116F7 CRC64;
MDDCEQVLLD LQQATLALDE QEETSPDVAE TMTALGSTVE LSSDMLHNAN INTNNDTNGN
NDIADTDSAD TTDTHCNATG AATSTANNDG SKDTTQDAAA ELAQLLEHAT VMPLDGCYGS
TPLDLGSAVM GSTTTRALIV RNTTARPQQV TIERFPFTKG FSLSVLSSSG EREAYDAGSA
SISFSLDAES EVTLFVGFTA PKTEEARSYR HVASFITGKR SYKLSLQVVA TVPLKPKPKR
TLRGAVGRTG LTRKHSLRAP LKAVNSANPS RLRTATTAKP QQRQTQRGNA AAAEGEKTMD
HKPIKPKAVK MPARKKKASP FADDTTQQES TQEPQVSAPS RFDRQERAYT TWINHVLSPA
RNVVNMHTER ELLKLRSRAK ALRASETVSN GLSKLWENIE GGALVAREES CIFLDIHLRD
EAVRVFMSFQ PEWLRFGLET LFAQPIEVDA SNPMSSLKAF VATNVMDNAD IKEHYCFPAV
PSHLVDEFHT TMANHILFTM IGVVFLVDQA RAKSLLPHSP CVFMPATFDS SNAVLAFISN
QFLKGEGSLE KHLRYLGLTF SYKQSSLEEY DYEVTNLSTD MRDGVKLWRV LSLMHSSNSS
RTALPYTPVV SQNKAVWVKN NKQYLAALKA AGCQQFFPQR AADDLANGHR DVTLSVLWAT
LVCFRICNPL DEALLLAEIA RIKRNPRYKR TDSRRASEAH MYQNSPQVNL LLQWCRAVCM
CYDLEVVDFT TSFSDGRALC YLINFYHPQL LQRSAINTST TATDTKDKTF DARMAAVRES
DNGFSCVMSP GVNRVGGRSR QQLLENEKGN YKLISQALKK LGGVPLLAKS KDMCGTVPDE
RVVISYVSCL CTRLLDINQE QRACLVIQRH WRRFHKRREE ELAVVKLQRQ WRSVLLMRAQ
QRAYQQTRTA VIALQSGVRM WRQRCAFQRT MHAIVAVQTC ARRWAARRVL AQLKRHHHAA
ITMQCAARAY IARRRTALLR EARDRHRAAT CIQRHILTWL ARTQHQQRCK AATAVQAVFR
GRQARRQAAR RRAAILVLQS RVRAVLLGRW IRTAYLQYKA AAVVLQRAWR QRCCLQATRA
VCQERRIAAT TIQSTWRMWK CKQQRRTRMT ALVTLQSFAR MFQAQRQLST LRRERAAAVT
LQAAVRGMRA RQVLRQTLTR RKETFAAVCI QKHVRGWRAR CAFTRTRTAT TTIQAALRGT
LARKEAQRRR SAIAVLQMHA RATLQMRGVR RGFLQFKTAA ITLQRQWRLR TEAKHTRQLC
VVRRNASVCI QRTWRMRRAR SHFLRLRSAA VVLQSAVRAT MARQHTAHLR RRQAVVQRVA
RGLHLNLCAI TIQRAFRGFA ARKTAAVVLQ KHARRHLAQT RFRRTLAAVV CLQRHTRGVA
TRRAYKAWRA QRLERLTGAT RAHLAATMIQ RGYRRYRQQT RAAVLMQKTV RGFLARRRFA
AVCTSVVRLQ CAWRCLQAVR EVRRRKEAAE RRARVLLLGA RMFLSTVTIQ RRVRAYQQRQ
REERAACVIQ RHFRVWKKLH SKACREGAAT RIQAWFRAYR IRKRMSDRLK RIHQNVMEVN
RQYCPEATLG WKTNSALTVL LKYKKVSRVL EALKNLNRMA GLSAECCGRI ASHDGLDVIY
TLIRSCNRSK PEMAMVVHCL SIIESLLRHD VTCERVMQNL QLGELMFDLT RGYRDNAEIF
EPACRLLHRC CQEPSHRERL QKDRSYMKRL ASLINMTERK ANVFIKAKTS ARKEEATSLL
ELVGLLKDIQ RTLNPQEQHN
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