ID F2UJW5_SALR5 Unreviewed; 1791 AA.
AC F2UJW5;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=PTSG_12745 {ECO:0000313|EMBL:EGD77414.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832977; EGD77414.1; -; Genomic_DNA.
DR RefSeq; XP_004990758.1; XM_004990701.1.
DR STRING; 946362.F2UJW5; -.
DR EnsemblProtists; EGD77414; EGD77414; PTSG_12745.
DR GeneID; 16071316; -.
DR KEGG; sre:PTSG_12745; -.
DR eggNOG; KOG0266; Eukaryota.
DR eggNOG; KOG3676; Eukaryota.
DR InParanoid; F2UJW5; -.
DR OMA; KGVCFTP; -.
DR OrthoDB; 198243at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19848:SF8; E3 UBIQUITIN-PROTEIN LIGASE TRAF7; 1.
DR PANTHER; PTHR19848; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF00400; WD40; 6.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00320; WD40; 10.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT TRANSMEM 962..982
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 994..1018
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1086..1104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1110..1130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1151..1172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1219..1240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 144..185
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 187..228
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 272..313
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 577..618
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 1081..1253
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 511..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1390..1442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1480..1791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1391..1407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1418..1437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1488..1562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1569..1588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1589..1615
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1616..1631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1640..1675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1703..1730
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1731..1745
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1791 AA; 195755 MW; FBED2EAF5B07662D CRC64;
MSSSSISSSS RRDKPGGRGR WISTANKFKV AEAFQSVGRR RMFRQVISRA KNIVAVRIFD
SDVCGIAVLH EDGQIILIDK GSGKIQYDTF IEAVETSIIK SAAFAHHANM IAVYTTKKRL
LIFDHGAEFN GFDAKLSINV VPLMEGKKCT LRVIVWSRDD ALVAAGGEDR VARVYDVRTG
VLVHRIANFH HDIIVGMDFH PTGRFLVTGS KDKHARVFDL SRSDPSLELE HNAEGRCYAV
VFSPDGSRLA VGADNNKTVL IDLKLQRVKQ TLEGHKDYVR AVMFTPDGRR ILTGGKDGQL
YFYDVATGQP LLPIRRIGWT VMMAQSTDGY QFVTAAQDKS SGPVLHLNIF NIFHDRSSDM
LMTMKLTSPV TALCFSKDGE KMFSGGKNGV VSMHDITTFQ EEAVLRLHTK PVSSIATAPS
GHVASASEDG SLVVFDSANP NDEVATVHVS KTPLTCTALS ACGRWLACAN VAGCLFIFDE
TNNLVCHHQV CDAPVSAIDF GFLERHGADA ASANDSSDRP AGNDDDDAGD ASAGMRNGSV
LIAVACHNKS TVVLDVADAV NEYLNDGIVE EAVRFVVTGH DKEVYSVRFS ADSSYLATGS
RDKTVRIVDV ETGQVIAKMV GHVDHVKGVC FTPKDEVVSV SLDGTCRVIP MDENVEDRNV
RFVELPSGAL CVDAAPTESR FAQLIAVGCS DSRICFIDLS FTNQQPLFRE AQMIAERAKA
TGDYTMMSAV VKRYPLVVHS EDRRGNTLCH YAVMQENDTL LNILLSAKLP EFWLPVNADG
ADILHLAVSN KSRSCVKLIL DCIISAKESG QLSRVPSRRD RFLRTLLQLA DEMDDLLALF
LKQFGLDDAP GVLKGDQLSL RSPRTVIMPS AIRLPEAHWN NLYEEDRLGE KDVGKVVRFQ
AKYLSIPNFA GLIRTSASAD PVSCLKDTVL HRFVRTGNAQ LFGNPLLKMV LDYKWQAYAR
SLFMRELGIF GGFLVTFTLF SLSAPRIDLS TSPVLSIFSD TTTVFSVLLA LVIPFFCYRQ
LKNEYRQVVR STAVRLVSGT AADDRSVGYE DDDDDDDDEA ALRSAMLTSP HANPTELVKA
VVLDGWNLLQ SGTATLALIS AVLFLFGSRW FIPVTSAASF FLWLEILYFL RAFEFTGGLV
RMVFKIFYYT GPFLLILVVV LLGTANCFHV LFSTIPSEDA LFQIDDSVMD SVFKTFKLLL
LGDGTVEEGL PPDDAVTGVV KLLFVVFMVG INIFMLNLMI NLMDDFMQKI NDEEGDAFPF
EKARIIAEIE LSMGDELLSN KTFFPRWLHM LTPKGGELGE REGIDEWQGT VQAIRAENMG
LERRTRDTLD RLQAHIITHF DAMEKRQTDR IGSLDDRVNN KIEALADSMN RMQAYQVALM
DALSGQTEAI ARARSHRSSS GSMRSPSAAI RSRRIRPQGK SPSASTASYS MPRSDAPDSA
NASVRRRFFK QAHSLDQSAS LIEPDYHLAD AHAHTTLVVP STAPGSLHGR SPRATTPSAV
IKAASASDVS SSGKAAVSRT ASGRKGTMTP STVTNGGSSD DLNLGSAPAS SASSSGTGGP
RSGSSVRRRV LPPRQNTTRA QHFRRDSTFS SGSDSRRESR TRSSLWDDDD ELVVYGDKSS
SSSSVTKESP TKLAPVNEVP NAGRSTTPPP SQRSTKRRLG RTRSNTGAGR LSRNLSRNSG
RKHGDGDGDG DGDGDGDDDN SEETVNNNSS SSSSNLHPND TQAHSANSTR DDNDGGAERR
ARLHTLRPMV SQPTIVARDE FDDDDDDLAD ELPASSQTIP DGFDSDKESM V
//
