ID F2UJX1_SALR5 Unreviewed; 566 AA.
AC F2UJX1;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Ubiquitin-activating enzyme SCCH domain-containing protein {ECO:0000259|Pfam:PF10585};
GN ORFNames=PTSG_08518 {ECO:0000313|EMBL:EGD77420.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification. {ECO:0000256|ARBA:ARBA00043952}.
CC -!- SIMILARITY: Belongs to the ubiquitin-activating E1 family.
CC {ECO:0000256|ARBA:ARBA00005673}.
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DR EMBL; GL832977; EGD77420.1; -; Genomic_DNA.
DR RefSeq; XP_004990764.1; XM_004990707.1.
DR AlphaFoldDB; F2UJX1; -.
DR EnsemblProtists; EGD77420; EGD77420; PTSG_08518.
DR GeneID; 16071322; -.
DR KEGG; sre:PTSG_08518; -.
DR InParanoid; F2UJX1; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR Gene3D; 1.10.10.2660; Ubiquitin-activating enzyme E1, SCCH domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR019572; UBA_E1_SCCH.
DR InterPro; IPR042063; Ubi_acti_E1_SCCH.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR Pfam; PF10585; UBA_E1_SCCH; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 21..77
FT /note="Ubiquitin-activating enzyme SCCH"
FT /evidence="ECO:0000259|Pfam:PF10585"
FT REPEAT 249..283
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 340..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 566 AA; 62942 MW; 247F934F357FE4D3 CRC64;
MQEKATEVSV WVADVPDFYG FFLYARTKSG EPFWSGHKIF PEALEFDPQN PLHKEFLIAV
TNLYACVFKV HPTKYPSEEN KLHIKRPPGS CPSASSEQGG YSYVNASPDG RLLVAESFMW
DMHRLTCKQR MPVTATDMVW TKDGRRPNLI CPSYSRVYIC GLGVREAERT VIFEDPFLGA
ELACAAAPDG TPWVIERWQK LGQPSTLLAE WRADVVGNGE ETIQDVGGEA ARGEVEAEPA
SKERKRTGVD ALRVTPDGRF LVTASTSTDL RVWDLSTLTP TRSATTQHEG TAAVAPTTTI
AATTTTRPFV FVVRPFADRS QKFVCACRNT LHVYVIEHRK HDDHQQDHQQ QQQRQQQQQQ
HVNGSSSGVS SALTRVAVLD GLFVDEVEPN ANMTVTTMAT HPTDDSLLAI GTARGDVFVC
DVANRKVLSK LKVSRNVPVK YSVFARHSSV LFVNSVESVI KCDYSTGQHS TILHRNDRAD
DMVMCDHQHL LTVSSSVSRG RVALWALGPT LNRAMIPTEQ FDLCHFRPTT DPRCRPYAIV
PIVVPPATPP ADAHKLDDYI SLHCRT
//
