ID F2ULP5_SALR5 Unreviewed; 546 AA.
AC F2ULP5;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=TNFR-Cys domain-containing protein {ECO:0000259|SMART:SM00208};
GN ORFNames=PTSG_09682 {ECO:0000313|EMBL:EGD78044.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; GL832980; EGD78044.1; -; Genomic_DNA.
DR RefSeq; XP_004990106.1; XM_004990049.1.
DR AlphaFoldDB; F2ULP5; -.
DR EnsemblProtists; EGD78044; EGD78044; PTSG_09682.
DR GeneID; 16070658; -.
DR KEGG; sre:PTSG_09682; -.
DR InParanoid; F2ULP5; -.
DR OrthoDB; 5348767at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR PANTHER; PTHR23097; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER; 1.
DR PANTHER; PTHR23097:SF181; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21-LIKE-RELATED; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR SMART; SM00208; TNFR; 2.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 216..251
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|SMART:SM00208"
FT DOMAIN 477..518
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|SMART:SM00208"
FT REGION 179..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 546 AA; 59510 MW; D479D18130EAD396 CRC64;
MDAGSTSRRI CIWWRRTRAV ASACIISQEH VCHPLSLAPQ VLGAAVNRGV ISTEMRAFNN
LNWHRGGGVL QKIGLTNPFF SGEYAAAHVT GCQDGPDKKC KKMAAGLRHV GAHSVETNRM
TFNGNISTFD LWDTETLHGG EDMELRETYF TTNGNLAQAV QQNRTAIHTV HNNTVRRARP
ADPTLTSSNG HCTSKWPDGK YELGQRQPHQ SRIAHCPLHY YAKDHGYVPC TTCGMGTWAS
APCSSSSDAV CSSWTECKPG QKESVSGNAV RDHRMCVSCT RGMEYQPLPD RASCFPTSVC
EEPFIETIPP TLTTDRLCSC DTLACNKLIT QLFEEMVCAE PTDEQLDVDG IRDTIRQMDA
YEARRSCPGC TDTCECSAGF ILVYDADSAD CRPCDGVTEF SPSVGGSKYE PIEECELGQE
EVAAPTRSSD RVCHDCSART IDLDSDGSTG CQPKCAPGFE EVQAMTLLIS DRVCDECPGG
HVQGCLWPAR ACSCFPVTTC DAGEEETAEP TPTSDRVCSQ CELGATFKPV ERPGRVMPPR
HAVRSG
//
