ID F2UQ27_SALR5 Unreviewed; 802 AA.
AC F2UQ27;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=PTSG_10680 {ECO:0000313|EMBL:EGD79695.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL832988; EGD79695.1; -; Genomic_DNA.
DR RefSeq; XP_004988645.1; XM_004988588.1.
DR AlphaFoldDB; F2UQ27; -.
DR STRING; 946362.F2UQ27; -.
DR EnsemblProtists; EGD79695; EGD79695; PTSG_10680.
DR GeneID; 16069181; -.
DR KEGG; sre:PTSG_10680; -.
DR eggNOG; KOG4626; Eukaryota.
DR InParanoid; F2UQ27; -.
DR OrthoDB; 2996504at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 3.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50005; TPR; 6.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 337..370
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 379..412
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 421..454
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 463..496
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 505..538
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 547..580
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 702..802
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 262..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..699
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 88328 MW; 31D6EB884DDFE006 CRC64;
MAAINASGVS AAAIRQFMAD LQQEFPGKYM AMTTQDACTA LVVPRTKEKQ RAYIDLMQEK
NGDDVAPATV FVSHAWRYKI VDVLSTLLEF AEEEEQAQHG GKETFFWFDL FVNNQHANVT
ANLPQEWWST TFKESIRQIG KVLLVLTPWN DPVPLTRAWC LWEIFCSISQ GDDVELAIRL
PSQQHVALRD AVLDDLAAVT DMLVHVQAEK AEAWKPEDKD MIFAAIEASV GFTALNKAVK
DQMRSWCLTT AEAFVTAMEQ QLQQQQQQQQ QQDEGGGEGG GEGGGGSAVD MMEYAKLCSQ
VGSVLSAFGA HTRAIELYHK DLDVTLDRLG EEHEQTALKY NNLGLAHTAR GDYATAIQYY
QRALRIKTAT LGANHESTGG THSNLGNVYD KVGDYERALQ QHEAALAILM ATVGEKDEET
AGAHGNLGST HFAMGDMDAA ILHYKTALRI FLDTCGRHHP QVARAYGNLG GAYRAVGDFA
NAVDCFQRDL EIKLAVLGEE HPETGIAYNN LGNAHNNLGQ REEALTCFEH ALHIFSAALG
DSHPHTAMVH GNLGSVYDET GNFQRAAESY GRAFAIQASV LGREHPHTAM TQERLATAYA
QHGDFARGLE HMQGAVQAFT TALGPQHRST VVAAKNLELM RNAAADAGFL VLAEGEQEAQ
APTDTGAKRQ RDTQHNPQHK DDDADENEGG GRGGDGDVRQ QHDMMCGWLQ KRGQLNTAFQ
PRFFRIVESS LLYFRGEDDT HPRGAIHLRA VKSVELKQGV GGDVPELHVA VPGRIFVFRL
DETHAITHDL HAWHRAFSDM LR
//
