ID F2URA4_SALR5 Unreviewed; 1411 AA.
AC F2URA4;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=PTSG_10886 {ECO:0000313|EMBL:EGD80207.1};
OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Salpingoeca.
OX NCBI_TaxID=946362 {ECO:0000313|Proteomes:UP000007799};
RN [1] {ECO:0000313|Proteomes:UP000007799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50818 {ECO:0000313|Proteomes:UP000007799};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "Annotation of Salpingoeca rosetta.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL832991; EGD80207.1; -; Genomic_DNA.
DR RefSeq; XP_004988269.1; XM_004988212.1.
DR STRING; 946362.F2URA4; -.
DR EnsemblProtists; EGD80207; EGD80207; PTSG_10886.
DR GeneID; 16068796; -.
DR KEGG; sre:PTSG_10886; -.
DR eggNOG; KOG3676; Eukaryota.
DR InParanoid; F2URA4; -.
DR OrthoDB; 1513505at2759; -.
DR Proteomes; UP000007799; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR024862; TRPV.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR10582:SF2; INACTIVE; 1.
DR PANTHER; PTHR10582; TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007799};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT TRANSMEM 1067..1088
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1108..1126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1138..1162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1199..1223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1274..1295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 241..287
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 463..498
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 1069..1306
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 771..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1411 AA; 155396 MW; 20D719B792C22B67 CRC64;
MAFKELPKRG ECAACPDNKS KAPVQLPRAH AASAARFDRN VHVELDQDSG SRERVDRIVV
PAHAEFVYCY TFNPLKARSN GTRYHPNLRR VWLGTGKVEH LSADLEECID LAFSPDTNCR
RLLQVFDTAV AVWNPLAEQG IASQRPVLLQ AVLPANARVD KELGDAFHLT QAVMTPSMDR
VIAFGNTDFV FAWARDYINA IATTCDGRIL ALGIKDLSKP VGEGHLVRLH DLASMTELAD
LQGHTDVITA LREVRTSSPG RAQWVCTASK DGTLKLWDTD RQECEATLAA VNPPFVQGYE
NTDIASGATV LPSPDGRFLV SRHPNATYLW DLARFECVKQ LACHGACAWL PGSKHLIGMS
GQTLLTFAAQ GVQEAERPRV VWNGSDCGAL CLTHDEQRAV VRQLCCVLVF DVHTSALLAR
TELPGNLESV FAVTRDDSHV AVSNKHSIHV LRLDNDLSED AVLQGHTRDV EHLTITYDGR
YLASGTRRGE MRLWDISNRA APTCIAIVAP LQSPDSPSFV AMAALPGAPR VAACTGDGSL
RVWAIGEEAQ RFRQALGQQA TAAQPGCQQS PSQQEAHCSS SEVPVTCVAT FATELKVATC
MAVKASDELV AVGGEKGTVK IYTLAQVLCQ TNHSSTDTPC TTLRIDTPSA LDCITFFPKA
ECLAALVRWE GAYMQRLTSH PQQHQPTVVI ARGLPDLLVV DSNNRVLLEQ WLSDIRALVV
VPVGPAIDHR RVPCHDPCVG SALRDRDLRE AMLRGAPAEW LQTLVPVNSA TTQELRNSSS
SSSSSSNHNN NNNNNNNNNS SSSSSSSNHN HSNSSNLTST STSTSNSNNH NDNDSSDYLP
LVAWLASLSD GAADLQAAFE AVQPGSLDLL TQPSMLRTAI TCSKDSRMVS HVTSIISRAV
HADACKRRHH AHHWFLDVRG LNTSFTEDLI ALIAGFPDQA AELLDSLGLV PLHTDHHYDH
QQTRLPESQM IVVGHERGYG EFFLWKRLRE GKVLHKLEDA GATPTLTEAC IVPIPYAAAF
LPGKEETSFL RALADKGKAE LFGSRIVRAV VQFKWETFGQ RRFLWEAAWY MLSLVLITVL
TFVFNASGKD LVQLLGAADN SSANASDISS VVIVALLAGM AFHDLVQEVR QVVAINNYLF
YVWNWMDLAS ISLIFVVVGT YFAGWVHARA FLALAVYLRW YRLLYYLQPF QSTGPLVRMI
LVICYDMRYF LLVLGISIVA AWTSFRLLLR DDSALPVEEL GDPANGLLLM FNMLLLADFD
LATFDGDYVV LLRILFVISM VLVPVVLLNL LIALMSDSYE RIQDRADIEF QLLRARILHE
QEKFMTKKEK RNPKLFPKWL HVLVPKGGAG SGGVQWQGVL HALKKEVAGV DNRVSGVERK
VEEQMADVQA KMEEALTLLK KLSEPQVPQQ E
//
